GAS7 and SFPQ

Number of citations of the paper that reports this interaction (PubMedID 16055720)
76

Data Source:
BioGRID (pull down)

		GAS7	SFPQ
Description		growth arrest specific 7	splicing factor proline and glutamine rich
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Speck Dendrite Paraspeckles RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Identical Protein Binding	Transcription Cis-regulatory Region Binding Nucleic Acid Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding
	Biological Process	Nervous System Development Cell Differentiation Clathrin Coat Assembly Neuron Projection Morphogenesis Clathrin-dependent Endocytosis	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Double-strand Break Repair Via Homologous Recombination Activation Of Innate Immune Response Immune System Process DNA Repair DNA Recombination Chromatin Remodeling Regulation Of DNA-templated Transcription MRNA Processing DNA Damage Response RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Innate Immune Response Positive Regulation Of Sister Chromatid Cohesion Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Chromosome Organization Regulation Of Cell Cycle Dendritic Transport Of Messenger Ribonucleoprotein Complex Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways			PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis
Drugs			Copper Artenimol
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Declining hemoglobin trajectory in blood donors ( 33491795) Glaucoma ( 31959993 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) Gut microbiota relative abundance (Prevotella) ( 33208821) Heel bone mineral density ( 30598549) Intraocular pressure ( 29785010 29617998 30054594 29235454 31798171 28073927 31959993 25173106 24002674 22570627) Medication use (antiglaucoma preparations and miotics) ( 31015401) Proteinuria and chronic kidney disease ( 26420894)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Endometrial cancer ( 21499250) Hip circumference ( 28552196)
Interacting Genes		28 interacting genes: ABI1 ACTA1 APBB1IP ATXN1L CDC37 CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH KHDRBS1 LSM4 MCRS1 MECOM MIR196B MYBPC2 NCKAP1 NCKAP1L NTAQ1 PACSIN1 PKNOX1 RPLP0 SF1 SF3A1 SFPQ WASF2 YIF1A	120 interacting genes: APBB1 AR CD2BP2 CEBPA CEP55 CPSF7 CSNK2A1 CTTN DDX17 DMRTB1 ERG ESR1 EXOSC5 EXOSC8 FHL2 FMR1 FUS FXR1 FXR2 GAS7 H3-4 JPT1 KRT31 LAMTOR5 LINC00624 LINC01554 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NONO OGT PIN1 PPARG PRPF40A PSPC1 PTBP1 RAC1 SF1 SF3B4 SIN3A SMAD5 SNRPA SREK1 TCERG1 TFIP11 TOP1 UBC UBE2I VIM WBP4 ZMYM2
Entrez ID		8522	6421
HPRD ID		16011	07284
Ensembl ID		ENSG00000007237	ENSG00000116560
Uniprot IDs		O60861	A0A384N5Z8 P23246 Q86VG2
PDB IDs		2LX7 2YSH	4WII 4WIJ 4WIK 5WPA 6NCQ 6OWJ 6WMZ 7LRQ 7LRU 7PU5 7SP0 7UJ1 7UK1
Enriched GO Terms of Interacting Partners?		SCAR Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Lamellipodium Lamellipodium Organization Positive Regulation Of Actin Nucleation Positive Regulation Of Lamellipodium Assembly Rac Protein Signal Transduction Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cytosol Cortical Actin Cytoskeleton Organization Actin Cytoskeleton Organization Positive Regulation Of Lamellipodium Organization Regulation Of Actin Nucleation Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Lamellipodium Assembly Regulation Of Lamellipodium Assembly MRNA 3'-splice Site Recognition Actin Filament-based Process Regulation Of Actin Filament Polymerization Lamellipodium Morphogenesis Cortical Cytoskeleton Organization Regulation Of Actin Filament Organization Small GTPase Binding Regulation Of Actin Polymerization Or Depolymerization Cell Projection Morphogenesis Regulation Of Actin Filament Length Regulation Of Lamellipodium Organization Cell Projection Dendrite Extension Cytoskeleton Organization Positive Regulation Of Organelle Organization Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Myeloid Cell Development Regulation Of Cytoskeleton Organization Hemopoiesis RNA 7-methylguanosine Cap Binding Regulation Of Actin Cytoskeleton Organization Extracellular Exosome Positive Regulation Of Cytoskeleton Organization Cell Morphogenesis Cell Projection Assembly MRNA Splicing, Via Spliceosome MRNA Cis Splicing, Via Spliceosome Actin Binding Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization RNA Splicing, Via Transesterification Reactions Regulation Of Organelle Organization Poly(U) RNA Binding	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Extracellular Vesicle Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Motility Regulation Of Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Locomotion Regulation Of MRNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Negative Regulation Of Angiogenesis Negative Regulation Of Cytokine Production Negative Regulation Of Vasculature Development Regulation Of Translation Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Angiogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Endothelial Cell Migration Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Developmental Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?