GAS7 and SF3A1

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		GAS7	SF3A1
Gene Name		growth arrest-specific 7	splicing factor 3a, subunit 1, 120kDa
Image
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Actin Filament	Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Actin Filament Binding	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Cell Cycle Arrest Regulation Of Cell Shape Actin Filament Polymerization Neuron Projection Morphogenesis Actin Filament Bundle Assembly	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Intraocular pressure ( 22570627)
Protein-Protein Interactions		22 interactors: ABI1 ACTA1 APBB1IP ATXN1L CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH HNRNPU KHDRBS1 NCKAP1 NCKAP1L PACSIN1 RPLP0 SF1 SF3A1 SFPQ WAS WASF2 WDYHV1	18 interactors: APBB1 CSNK2A1 DDX42 GAS7 IL7R PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 TCERG1 UBC WBP4 WDR77
Entrez ID		8522	10291
HPRD ID		16011	06903
Ensembl ID		ENSG00000007237	ENSG00000099995
Uniprot IDs		B7Z1Q2 O60861	E9PAW1 Q15459
PDB IDs		2LX7 2YSH	1ZKH 2DT6 2DT7
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Cytoskeleton Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Lamellipodium Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Rac Protein Signal Transduction Regulation Of Arp2/3 Complex-mediated Actin Nucleation Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Actin Nucleation Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Phagocytosis Fc Receptor Signaling Pathway Actin Filament Organization MRNA Metabolic Process Lamellipodium Morphogenesis MRNA 3'-splice Site Recognition Positive Regulation Of Immune System Process Lamellipodium Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Immune Response Endocytosis Cellular Component Assembly Actin Filament-based Movement Regulation Of Actin Filament-based Process Positive Regulation Of Cytoskeleton Organization Organelle Organization MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Actin Polymerization Or Depolymerization Innate Immune Response Regulation Of Cytoskeleton Organization Cellular Response To Stimulus Positive Regulation Of Lamellipodium Assembly Regulation Of Immune Response Megakaryocyte Development Regulation Of Immune System Process Positive Regulation Of Lamellipodium Organization RNA Processing Regulation Of Cellular Component Organization Vesicle-mediated Transport Megakaryocyte Differentiation Regulation Of Lamellipodium Assembly Movement Of Cell Or Subcellular Component	RNA Splicing RNA Processing MRNA Processing RNA Metabolic Process MRNA Metabolic Process MRNA 3'-splice Site Recognition Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splice Site Selection Cellular Macromolecular Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Ribonucleoprotein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Spliceosomal Complex Assembly Negative Regulation Of Cell Cycle DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cell Cycle Arrest Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Biosynthetic Process Cell Cycle Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Gland Development Cellular Metabolic Process Negative Regulation Of BMP Signaling Pathway
Tagcloud ?		as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc glaugen human660w interrogated kilobases lrp12 merit myoc neighbor optn penncnv poag quad six1 six6 srbd1 tmco1 wdr36 zfpm2	actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2
Tagcloud (Difference) ?		as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc glaugen human660w interrogated kilobases lrp12 merit myoc neighbor optn penncnv poag quad six1 six6 srbd1 tmco1 wdr36 zfpm2	actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2
Tagcloud (Intersection) ?