RAB11FIP2 and REPS1

Number of citations of the paper that reports this interaction (PubMedID 12364336)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vitro, in vivo)

		RAB11FIP2	REPS1
Description		RAB11 family interacting protein 2	RALBP1 associated Eps domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Endosome Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cell Projection Recycling Endosome Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity	Calcium Ion Binding Protein Binding SH3 Domain Binding Protein-macromolecule Adaptor Activity Metal Ion Binding
	Biological Process	Phagocytosis Cell Communication Protein Transport Vesicle-mediated Transport Signaling Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane	Endocytosis Endosomal Transport
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 29403010 30993211)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834) Type 2 diabetes ( 32499647)
Interacting Genes		22 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B OGT PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 SNCA YWHAE YWHAG	19 interacting genes: AKT1 ANKRD1 ATF4 CRK FLNC GRB2 HSF1 ITSN1 ITSN2 MZT1 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2 TRAPPC2L WWC2
Entrez ID		22841	85021
HPRD ID		10548	09687
Ensembl ID		ENSG00000107560	ENSG00000135597
Uniprot IDs		Q7L804	B2R7D3 Q96D71
PDB IDs		2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endosomal Transport Endocytosis Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Import Into Cell Intracellular Protein Localization Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Intracellular Transport Myosin V Binding Organelle Localization Establishment Of Protein Localization Regulation Of Endocytic Recycling Endocytic Recycling Regulation Of Biological Quality Vesicle-mediated Transport In Synapse Exocytosis Recycling Endosome Membrane Cellular Localization Secretion By Cell Establishment Of Vesicle Localization Protein Localization To Organelle Synaptic Vesicle Endocytosis Vesicle Localization Protein Sequestering Activity Regulation Of Intracellular Transport Presynaptic Endocytosis Synaptic Vesicle Membrane Synaptic Vesicle Amyloid-beta Clearance By Transcytosis Regulation Of Synapse Organization Secretion Protein Transport Cytoplasm Regulation Of Cellular Localization Positive Regulation Of Endocytosis Postsynaptic Endocytic Zone Glutamatergic Synapse Receptor-mediated Endocytosis GTP Binding Receptor Internalization Regulation Of Transport Clathrin-coated Pit G Protein Activity Regulation Of Protein Localization Protein-macromolecule Adaptor Activity Regulation Of SNARE Complex Assembly Phagocytic Vesicle Protein Localization To Endoplasmic Reticulum	Vesicle-mediated Transport Endocytosis Receptor-mediated Endocytosis Intracellular Signaling Cassette Import Into Cell Intracellular Signal Transduction Clathrin-dependent Synaptic Vesicle Endocytosis Cytosol Protein-macromolecule Adaptor Activity Small GTPase-mediated Signal Transduction Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Regulation Of Signal Transduction Positive Regulation Of Organelle Organization Signal Transduction Organelle Organization Cellular Response To Decreased Oxygen Levels Response To Decreased Oxygen Levels Regulation Of Organelle Organization Cellular Response To Oxygen Levels Response To Oxygen Levels Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling PERK-mediated Unfolded Protein Response Receptor Internalization Establishment Of Protein Localization To Mitochondrion General Transcription Initiation Factor Binding TRAPPII Protein Complex TRAPPIII Protein Complex ERBB Signaling Pathway Ras Protein Signal Transduction Regulation Of Innate Immune Response Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Kinase Binding Cellular Localization Positive Regulation Of Protein Localization To Membrane Regulation Of Intracellular Signal Transduction TRAPP Complex Cytoplasm Positive Regulation Of Growth Positive Regulation Of Organelle Assembly Kinase Binding Positive Regulation Of Cellular Component Biogenesis Intracellular Vesicle Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Organization Response To Hypoxia
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