RAB11FIP2 and RAB11FIP4

Number of citations of the paper that reports this interaction (PMID 12470645)
18

Data Source:
HPRD (in vitro)

		RAB11FIP2	RAB11FIP4
Gene Name		RAB11 family interacting protein 2 (class I)	RAB11 family interacting protein 4 (class II)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Endosome Plasma Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Extracellular Space Endosome Endocytic Vesicle Midbody Cleavage Furrow Recycling Endosome Membrane
	Molecular Function	Protein Binding Rab GTPase Binding Protein Kinase Binding Protein Homodimerization Activity	Calcium Ion Binding Protein Binding Rab GTPase Binding ADP-ribosylation Factor Binding Protein Homodimerization Activity
	Biological Process	Renal Water Homeostasis Water Transport Protein Transport Establishment Of Cell Polarity Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Secretory Pathway Transmembrane Transport	Cytokinesis Transport Viral Process
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: AP2A1 CXCR2 EHD1 ITSN1 MARK2 MYO5B RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAG	7 interactors: ARF6 GFI1B KIAA0368 RAB11A RAB11FIP2 RAB11FIP3 RAB11FIP5
Entrez ID		22841	84440
HPRD ID		10548	11466
Ensembl ID		ENSG00000107560	ENSG00000131242
Uniprot IDs		Q3I768 Q7L804	Q86YS3
PDB IDs		2GZD 2GZH 2K6S 3TSO 4C4P
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Organelle Localization Cellular Localization Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Regulation Of Endocytic Recycling Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Protein Transport Endosomal Transport Vesicle Localization Cellular Pigmentation Rab Protein Signal Transduction Endocytosis Protein Localization Establishment Of Organelle Localization Establishment Of Localization In Cell Cellular Protein Localization Pigmentation Regulation Of Vesicle-mediated Transport Chemical Homeostasis Nervous System Development Intracellular Transport Generation Of Neurons Neurogenesis Renal Water Homeostasis Intracellular Signal Transduction Cellular Response To Organic Substance Cell Projection Organization Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Water Transport Fluid Transport Multicellular Organismal Water Homeostasis Homeostatic Process Water Homeostasis Cell Differentiation Positive Regulation Of Cell Migration Neuron Projection Development Negative Regulation Of Neutrophil Apoptotic Process Multivesicular Body Assembly Regulation Of Multivesicular Body Size Positive Regulation Of Cell Motility Exocytosis Positive Regulation Of Cellular Component Movement Receptor-mediated Endocytosis	Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle-mediated Transport Renal Water Homeostasis Insulin Secretion Water Transport Fluid Transport Multicellular Organismal Water Homeostasis Exocytosis Regulated Secretory Pathway Cellular Response To Glucose Stimulus Water Homeostasis Peptide Hormone Secretion Peptide Secretion Cell Division Cellular Localization Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Hormone Secretion Multivesicular Body Assembly Regulation Of Multivesicular Body Size Secretion By Cell Hormone Transport Peptide Transport Renal System Process Protein Transport Cytokinesis Establishment Of Protein Localization Establishment Of Cell Polarity Protein Secretion Multivesicular Body Organization Secretion Amide Transport Response To Glucose Regulation Of Endosome Size Exosomal Secretion Regulation Of Protein Localization Protein Localization Establishment Or Maintenance Of Cell Polarity Response To Carbohydrate Establishment Of Localization In Cell Chemical Homeostasis Glucose Homeostasis Endosomal Transport Myeloid Cell Apoptotic Process Cellular Response To Acidic PH Plasma Membrane To Endosome Transport Astral Microtubule Organization Regulation Of Hormone Levels Protein Localization To Endosome Regulation Of Cellular Component Size
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