RAB11FIP2 and RAB25

Number of citations of the paper that reports this interaction (PMID 11495908)
79

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		RAB11FIP2	RAB25
Gene Name		RAB11 family interacting protein 2 (class I)	RAB25, member RAS oncogene family
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Endosome Plasma Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Cytoplasmic Membrane-bounded Vesicle Pseudopodium Pseudopodium Membrane Cytoplasmic Vesicle Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Protein Kinase Binding Protein Homodimerization Activity	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Renal Water Homeostasis Water Transport Protein Transport Establishment Of Cell Polarity Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Secretory Pathway Transmembrane Transport	Epithelial Cell Morphogenesis Intracellular Protein Transport Exocytosis Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial Cell Migration Pseudopodium Organization Melanosome Transport Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: AP2A1 CXCR2 EHD1 ITSN1 MARK2 MYO5B RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAG	13 interactors: ACVR1 BMPR1B ITGB1 MED31 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SMAD4 SMURF2 TGFBR1
Entrez ID		22841	57111
HPRD ID		10548	06698
Ensembl ID		ENSG00000107560	ENSG00000132698
Uniprot IDs		Q3I768 Q7L804	P57735
PDB IDs		2GZD 2GZH 2K6S 3TSO 4C4P	2OIL 3TSO
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Organelle Localization Cellular Localization Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Regulation Of Endocytic Recycling Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Protein Transport Endosomal Transport Vesicle Localization Cellular Pigmentation Rab Protein Signal Transduction Endocytosis Protein Localization Establishment Of Organelle Localization Establishment Of Localization In Cell Cellular Protein Localization Pigmentation Regulation Of Vesicle-mediated Transport Chemical Homeostasis Nervous System Development Intracellular Transport Generation Of Neurons Neurogenesis Renal Water Homeostasis Intracellular Signal Transduction Cellular Response To Organic Substance Cell Projection Organization Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Water Transport Fluid Transport Multicellular Organismal Water Homeostasis Homeostatic Process Water Homeostasis Cell Differentiation Positive Regulation Of Cell Migration Neuron Projection Development Negative Regulation Of Neutrophil Apoptotic Process Multivesicular Body Assembly Regulation Of Multivesicular Body Size Positive Regulation Of Cell Motility Exocytosis Positive Regulation Of Cellular Component Movement Receptor-mediated Endocytosis	Response To Transforming Growth Factor Beta BMP Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulated Secretory Pathway Endocardial Cell Differentiation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Endothelial Cell Activation Response To Growth Factor Positive Regulation Of SMAD Protein Import Into Nucleus Cell Fate Commitment Germ Cell Migration Negative Regulation Of Cell Proliferation Cellular Response To Organic Substance Regulation Of SMAD Protein Import Into Nucleus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Mesenchymal Cell Development Endocardium Development Atrioventricular Valve Morphogenesis Pharyngeal System Development Cardiocyte Differentiation Mesenchymal Cell Differentiation Atrioventricular Valve Development Protein Transport Mesoderm Development Vesicle-mediated Transport Establishment Of Protein Localization Cardiac Epithelial To Mesenchymal Transition Enzyme Linked Receptor Protein Signaling Pathway Pattern Specification Process Activin Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Ameboidal-type Cell Migration Cellular Localization Renal Water Homeostasis In Utero Embryonic Development Heart Development Gastrulation Regulation Of Cellular Response To Growth Factor Stimulus Heart Valve Morphogenesis Response To Organic Substance Heart Valve Development Cell Cycle Process Mesenchyme Development
Tagcloud ?			acini acquire alpha5beta1 basement cargo clic3 com compartments concert correspondingly drives endosomal endosomes integrin invasiveness matrigel mcf10dcis metalloproteinase mmp mmp14 mt1 opposes organotypic plane plugs predicts recycling trafficking transferred
Tagcloud (Difference) ?			acini acquire alpha5beta1 basement cargo clic3 com compartments concert correspondingly drives endosomal endosomes integrin invasiveness matrigel mcf10dcis metalloproteinase mmp mmp14 mt1 opposes organotypic plane plugs predicts recycling trafficking transferred
Tagcloud (Intersection) ?