ATG4D and GABARAPL1

Number of citations of the paper that reports this interaction (PubMedID 19549685)
47

Data Source:
BioGRID (enzymatic study)

		ATG4D	GABARAPL1
Description		autophagy related 4D cysteine peptidase	GABA type A receptor associated protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Cysteine-type Endopeptidase Activity Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Protein-phosphatidylethanolamide Deconjugating Activity Cysteine-type Exopeptidase Activity	Protein Binding Phospholipid Binding Phosphatidylethanolamine Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Autophagosome Assembly Mitophagy Proteolysis Autophagy Apoptotic Process Protein Transport Protein Processing Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Aggrephagy Protein Delipidation	Autophagosome Assembly Mitophagy Autophagy Cellular Response To Nitrogen Starvation Glycophagy Autophagosome Maturation
Pathways		Macroautophagy	Macroautophagy
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: CASP3 CASP8 GABARAP GABARAPL1 GABARAPL2 MAP1LC3B TRIM55	87 interacting genes: AHNAK2 AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG4A ATG4B ATG4D AZI2 BICC1 BNIP3L BRD9 BSCL2 BSDC1 CALCOCO1 CALCOCO2 CARS2 CCT2 CDC37 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 G3BP1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAP4K2 MAPK15 MEFV MLX MYBPC1 NCOR1 NEDD4 NFIA NUFIP2 OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RESF1 RETREG3 SCYL3 SEC62 SNCA SQSTM1 SRPK1 SRPK2 STK3 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM25 TRIM32 UMAD1 VDR WDFY3 ZBTB22
Entrez ID		84971	23710
HPRD ID		07005	07601
Ensembl ID		ENSG00000130734	ENSG00000139112
Uniprot IDs		B4DGM8 Q86TL0	Q9H0R8
PDB IDs			2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL 6YOO 7AA7 7AA9 7JHX 8X8A
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Autophagosome Maturation Vacuole Organization Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome GABA Receptor Binding Ubiquitin Protein Ligase Binding Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Beta-tubulin Binding Cellular Response To Starvation Response To Starvation Response To Anesthetic Cellular Response To Nutrient Levels Death-inducing Signaling Complex Organelle Assembly Autophagy Positive Regulation Of Pyroptotic Inflammatory Response Response To Cobalt Ion Microtubule Death Receptor Binding Response To Nutrient Levels Response To Stress Execution Phase Of Apoptosis Pyroptotic Inflammatory Response Microtubule Binding Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Organelle Organization Cellular Response To Stress Apoptotic Signaling Pathway Cytoplasmic Vesicle Cysteine-type Endopeptidase Activity Positive Regulation Of Neuron Apoptotic Process Regulation Of Proteolysis Catabolic Process Phospholipase A2 Activator Activity Response To Estradiol Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Positive Regulation Of Protein K48-linked Ubiquitination Axoneme Cysteine-type Peptidase Activity	Autophagosome Regulation Of Cilium Assembly Autophagy Macroautophagy GTPase Activator Activity Regulation Of Organelle Assembly Cytosol Regulation Of Autophagy Positive Regulation Of Autophagy Autophagy Of Mitochondrion Regulation Of Cell Projection Assembly Mitophagy Autophagosome Assembly Autophagosome Organization Aggrephagy Cytoplasmic Vesicle Piecemeal Microautophagy Of The Nucleus Cytoplasm Regulation Of Cell Projection Organization Microautophagy Nucleophagy Positive Regulation Of Catabolic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Vacuole Organization Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Protein-phosphatidylethanolamide Deconjugating Activity Catabolic Process Protein Delipidation Response To Mitochondrial Depolarisation Organelle Assembly Regulation Of Macroautophagy Atg1/ULK1 Kinase Complex Regulation Of Cellular Component Organization Positive Regulation Of Macroautophagy Regulation Of Intracellular Signal Transduction Protein Polyubiquitination Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Signal Transduction Phagophore Assembly Site Negative Regulation Of Signal Transduction ERBB3:ERBB2 Complex Protein Localization To Phagocytic Vesicle Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Response To Stress Regulation Of Signaling Regulation Of Cell Communication Negative Regulation Of Viral Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?