ATG4D

Description		autophagy related 4D cysteine peptidase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Cysteine-type Endopeptidase Activity Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Protein-phosphatidylethanolamide Deconjugating Activity Cysteine-type Exopeptidase Activity
	Biological Process	Autophagosome Assembly Mitophagy Proteolysis Autophagy Apoptotic Process Protein Transport Protein Processing Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Aggrephagy Protein Delipidation
Pathways		Macroautophagy
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: TIMM29
Interacting Genes		7 interacting genes: CASP3 CASP8 GABARAP GABARAPL1 GABARAPL2 MAP1LC3B TRIM55
Entrez ID		84971
HPRD ID		07005
Ensembl ID		ENSG00000130734
Uniprot IDs		B4DGM8 Q86TL0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Autophagosome Maturation Vacuole Organization Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome GABA Receptor Binding Ubiquitin Protein Ligase Binding Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Beta-tubulin Binding Cellular Response To Starvation Response To Starvation Response To Anesthetic Cellular Response To Nutrient Levels Death-inducing Signaling Complex Organelle Assembly Autophagy Positive Regulation Of Pyroptotic Inflammatory Response Response To Cobalt Ion Microtubule Death Receptor Binding Response To Nutrient Levels Response To Stress Execution Phase Of Apoptosis Pyroptotic Inflammatory Response Microtubule Binding Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Organelle Organization Cellular Response To Stress Apoptotic Signaling Pathway Cytoplasmic Vesicle Cysteine-type Endopeptidase Activity Positive Regulation Of Neuron Apoptotic Process Regulation Of Proteolysis Catabolic Process Phospholipase A2 Activator Activity Response To Estradiol Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Positive Regulation Of Protein K48-linked Ubiquitination Axoneme Cysteine-type Peptidase Activity
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