ATG4D

Gene Name		autophagy related 4D, cysteine peptidase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Cytosol
	Molecular Function	Cysteine-type Endopeptidase Activity
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation C-terminal Protein Lipidation Proteolysis Protein Targeting To Membrane Apoptotic Process Cellular Response To Nitrogen Starvation Protein Processing Nucleophagy Protein Delipidation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CASP3 CASP8 GABARAPL1 GABARAPL2
Entrez ID		84971
HPRD ID		07005
Ensembl ID		ENSG00000130734
Uniprot IDs		B4DGM8 Q86TL0
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleophagy Mitochondrion Degradation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Organelle Disassembly Mitochondrion Organization Autophagic Vacuole Assembly Macroautophagy Catabolic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Zymogen Activation Vacuole Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Response To Tumor Necrosis Factor Membrane Fusion Positive Regulation Of Endopeptidase Activity Cellular Response To Starvation Positive Regulation Of Peptidase Activity Autophagy Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Positive Regulation Of Hydrolase Activity Cellular Response To Nutrient Levels Response To Starvation Intrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Response To Stress TRAIL-activated Apoptotic Signaling Pathway Cellular Response To Extracellular Stimulus Protein Processing Myeloid Cell Differentiation Positive Regulation Of Proteolysis Cellular Response To Stress Positive Regulation Of Catalytic Activity Glial Cell Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Apoptotic Signaling Pathway Regulation Of Endopeptidase Activity Response To External Stimulus Regulation Of Peptidase Activity Response To Nutrient Levels Positive Regulation Of Macrophage Differentiation Cellular Component Assembly Negative Regulation Of Activated T Cell Proliferation Response To Cobalt Ion
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