RAE1 and BUB1

Number of citations of the paper that reports this interaction (PMID 11352911)
33

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		RAE1	BUB1
Gene Name		ribonucleic acid export 1	BUB1 mitotic checkpoint serine/threonine kinase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Outer Membrane Nuclear Pore Nucleolus Cytoplasm Cytoskeleton	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	RNA Binding Microtubule Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Transmembrane Transport Cellular Response To Organic Cyclic Compound	Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Chromosome Segregation Regulation Of Sister Chromatid Cohesion Mitotic Nuclear Division Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Proliferation Viral Process Cell Division Regulation Of Chromosome Segregation Spindle Assembly Checkpoint Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BUB1 DDX24 KLRC4 KLRK1 NUMA1 NUP98 NXF1	18 interactors: AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BUB1B BUB3 CASC5 CDC20 CDK1 CRK EIF4EBP1 HDAC1 PLK1 RAE1 RDH12 SVIL
Entrez ID		8480	699
HPRD ID		11939	03907
Ensembl ID			ENSG00000169679
Uniprot IDs		P78406	B4DYG2 E9PC26 F5GXI5 O43683
PDB IDs		3MMY	2LAH 3E7E 4A1G
Enriched GO Terms of Interacting Partners?		Viral Process MRNA Transport Nucleus Organization Protein Import Into Nucleus, Docking RNA Transport Mitotic Cell Cycle Process RNA Localization Mitotic Cell Cycle Nuclear Pore Complex Assembly Nucleocytoplasmic Transport Cell Cycle Process Nuclear Transport Nuclear Pore Organization Poly(A)+ MRNA Export From Nucleus Pore Complex Assembly Mitotic Nuclear Division	Spindle Assembly Checkpoint Spindle Checkpoint Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Mitotic Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Cell Cycle Checkpoint Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Mitotic Cell Cycle Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Mitotic Cell Cycle Checkpoint Mitotic Nuclear Division Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Chromosome Segregation Negative Regulation Of Cell Division Regulation Of Ubiquitin-protein Transferase Activity Protein Localization To Chromosome Negative Regulation Of Chromosome Organization Regulation Of Cell Cycle Cell Cycle Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Cell Division Cell Cycle Process Negative Regulation Of Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Negative Regulation Of Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Mitotic Nuclear Division Protein Localization To Kinetochore Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Localization To Chromosome, Centromeric Region Negative Regulation Of Mitotic Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Localization Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination
Tagcloud ?		constitutively cytosolic ddr effector emu enabling express immunoreceptor immunosurveillance irf3 killer ligands myc nk nkg2d nkg2dl occurrence originally recognizes relies revealing sensor sting sufficient tbk1 thereby transcript transfection upregulated	aneuploidy apocrine arp2 beta1 biomarker box broad cytokinesis exploring forkhead foxm1 inside integrin luminal m1 microtubule mitosis mitotic notable partners pip polymerization prolactin proteomic rationale signature silencing talin tubulin
Tagcloud (Difference) ?		constitutively cytosolic ddr effector emu enabling express immunoreceptor immunosurveillance irf3 killer ligands myc nk nkg2d nkg2dl occurrence originally recognizes relies revealing sensor sting sufficient tbk1 thereby transcript transfection upregulated	aneuploidy apocrine arp2 beta1 biomarker box broad cytokinesis exploring forkhead foxm1 inside integrin luminal m1 microtubule mitosis mitotic notable partners pip polymerization prolactin proteomic rationale signature silencing talin tubulin
Tagcloud (Intersection) ?