OGT and CCNB1

Number of citations of the paper that reports this interaction (PubMedID 32994395)
54

Data Source:
BioGRID (pull down)

		OGT	CCNB1
Description		O-linked N-acetylglucosamine (GlcNAc) transferase	cyclin B1
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane Protein N-acetylglucosaminyltransferase Complex Mitochondrial Membrane Protein-containing Complex Cell Projection NSL Complex Synapse Sin3-type Complex Glutamatergic Synapse	Spindle Pole Outer Kinetochore Nucleus Nucleoplasm Cytoplasm Mitochondrial Matrix Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Membrane Cyclin B1-CDK1 Complex
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding Acetylglucosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Chromatin DNA Binding Protein O-acetylglucosaminyltransferase Activity	Patched Binding Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Kinase Binding Ubiquitin-like Protein Ligase Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitophagy Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Cytoplasmic Translation Regulation Of Glycolytic Process Regulation Of Gluconeogenesis Chromatin Organization Regulation Of Transcription By RNA Polymerase II Protein Glycosylation Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Protein Processing Negative Regulation Of Translation Hemopoiesis Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein Ubiquitination Cellular Response To Nutrient Levels Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction TORC1 Signaling Positive Regulation Of Translation Positive Regulation Of Proteolysis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Lipid Biosynthetic Process Rhythmic Process Protein Maturation Regulation Of Synapse Assembly Regulation Of Necroptotic Process Protein Localization To Lysosome Pyroptotic Inflammatory Response Cellular Response To Glucose Stimulus Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Cold-induced Thermogenesis Membraneless Organelle Assembly Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of TORC1 Signaling	G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Oocyte Maturation In Utero Embryonic Development Mitotic Spindle Organization Mitotic Metaphase Chromosome Alignment Spermatogenesis Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Toxic Substance Negative Regulation Of Gene Expression Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of MRNA 3'-end Processing Tissue Regeneration Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Response To DDT Positive Regulation Of Fibroblast Proliferation Digestive Tract Development Cell Division Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Ventricular Cardiac Muscle Cell Development Positive Regulation Of Cardiac Muscle Cell Proliferation Regulation Of Chromosome Condensation Protein-containing Complex Assembly Cellular Response To Iron(III) Ion Cellular Response To Fatty Acid Cellular Response To Hypoxia Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport
Pathways		HATs acetylate histones RIPK1-mediated regulated necrosis Regulation of necroptotic cell death UCH proteinases Formation of WDR5-containing histone-modifying complexes	E2F-enabled inhibition of pre-replication complex formation Polo-like kinase mediated events Golgi Cisternae Pericentriolar Stack Reorganization APC/C:Cdc20 mediated degradation of Cyclin B Regulation of APC/C activators between G1/S and early anaphase Phosphorylation of the APC/C Phosphorylation of Emi1 Condensation of Prophase Chromosomes MASTL Facilitates Mitotic Progression Resolution of Sister Chromatid Cohesion Condensation of Prometaphase Chromosomes Regulation of PLK1 Activity at G2/M Transition Activation of NIMA Kinases NEK9, NEK6, NEK7 Initiation of Nuclear Envelope (NE) Reformation Nuclear Pore Complex (NPC) Disassembly Depolymerization of the Nuclear Lamina TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Mitotic Prophase Cyclin A/B1/B2 associated events during G2/M transition G2/M DNA replication checkpoint Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex The role of GTSE1 in G2/M progression after G2 checkpoint Transcriptional regulation by RUNX2 Nuclear events stimulated by ALK signaling in cancer Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Drugs
Diseases
GWAS		Red cell distribution width ( 32888494)
Interacting Genes		717 interacting genes: - AAMP AARSD1 AASS ABI1 ABI2 ABRAXAS1 ABRAXAS2 ACOX1 ACTB ACTC1 ACTL6A ACTR3 ADPGK ADSL AGFG1 AHSA1 ALDH1A2 ALDH1B1 ALDH2 ALDH4A1 ALDH5A1 ALDH6A1 ALDH7A1 ALDOA ALKBH5 ANAPC7 ANXA11 ANXA6 ANXA7 API5 APMAP APOH ARHGAP1 ARHGAP19 ARIH2 ARMC6 ASCC1 ASPH ATAD3A ATIC ATL2 ATL3 ATP1B1 ATP1B3 ATP5F1A ATP5F1B ATP6AP1 ATXN10 ATXN2L B3GLCT B4GAT1 BAG1 BAIAP2 BCCIP BCLAF1 BEND7 BIRC5 BSG BTG3 BYSL BZW2 C17orf75 CAAP1 CALR CARS2 CASP8 CAT CAVIN1 CBLL1 CBR1 CCDC47 CCDC77 CCDC86 CCNB1 CCT2 CCT3 CCT4 CCT5 CCT6A CCT7 CCT8 CD2BP2 CDC37 CDC42EP1 CDC5L CDC6 CDK9 CDKAL1 CELF1 CENPU CEP43 CEP55 CEP57 CHMP7 CHST7 CIRSR CKAP4 CKB CKMT1A CLCC1 CLN5 CLPB CLPX CNDP2 CNOT11 COIL COPS2 COQ8B CPSF6 CPSF7 CREBBP CRTAP CSNK1G2 CSNK2A1 CSNK2B CTSD CTU2 CWC25 CWC27 CXADR DAPK3 DAZAP1 DBN1 DBNL DBT DCTN2 DDX17 DDX28 DDX39B DDX3X DDX41 DDX47 DDX5 DDX56 DEK DHX30 DHX9 DLD DLG3 DLST DMAP1 DNAJA1 DNAJA2 DNAJC3 DNAJC7 DUS1L DYNC1LI1 DYNC1LI2 EARS2 ECSIT EDC3 EEF1A1 EEF1G EHD1 EIF2AK2 EIF2S2 EIF3D EIF3E EIF3F EIF3G EIF4A1 EIF4G2 EIF5 ELOA ENO1 ERGIC3 ERI1 ERO1A ERO1B ESS2 ETF1 EWSR1 FAF2 FAM199X FAM98A FARSA FDXR FEN1 FH FILNC1 FIP1L1 FIZ1 FKBP10 FKBP4 FKBP5 FKBP8 FNTA FTO FTSJ3 FUBP3 FUCA1 FUCA2 FUS G3BP1 G3BP2 GABPA GAPDH GART GATA6 GATB GBA1 GDI1 GDI2 GLA GLMN GLS GLUD1 GNL3 GORASP2 GPATCH4 GPKOW GPS1 GPT2 GRSF1 GRWD1 GSK3A GSK3B GSS GSTM3 GSTP1 GTF2E1 GTF2H1 GTF3C5 GTPBP3 GXYLT1 H1-4 HABP4 HARS1 HARS2 HAUS8 HCFC1 HGH1 HIRA HIVEP1 HMGCS1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPM HNRNPR HP1BP3 HS2ST1 HSP90AB1 HSP90B1 HSPA13 HSPA14 HSPA1A HSPA9 HSPD1 IFRD2 IGF2BP1 IGF2BP2 IGF2BP3 IGKV2D-29 IK IKBIP ILF2 ILF3 ILK ILKAP IMPDH1 IMPDH2 IPO5 IRF3 IRS4 IST1 ISYNA1 JMJD6 KARS1 KATNA1 KHDRBS1 KHDRBS3 KNOP1 KPNA1 KPNA2 KPNA3 KPNA4 KPNA6 KPNB1 KRR1 KRT1 KRT10 KRT2 KRT8 KRT9 LACTB LAP3 LARP4B LDHB LEMD2 LENG9 LETM1 LMAN1 LMNA LNPK LPCAT1 LPCAT4 LRP4 LRRFIP2 LSM14A LSM14B LSR LTV1 LUC7L2 LUC7L3 LYAR MAP1A MAP7D1 MAPT MARS2 MAT2A MAZ MCCC2 ME1 ME2 MEAK7 METAP2 MFAP1 MICU1 MINPP1 MPP1 MRM3 MSTO1 MTDH MYEF2 NAE1 NAMPT NAP1L1 NAP1L4 NASP NCL NDUFV1 NELFCD NHERF1 NISCH NKAP NOC4L NOLC1 NOM1 NONO NOP53 NOP58 NPM1 NSMCE4A NSUN5 NSUN6 NT5DC1 NUDC NUF2 NUFIP1 NUFIP2 NUP50 NUP54 NUP62 NUP62CL NUSAP1 NXN OAT OCLN OGA OLA1 OXCT1 OXSR1 P3H4 P4HA1 P4HA2 P4HB PA2G4 PABPC1 PABPC4 PABPN1 PACSIN3 PAIP1 PAK2 PALS2 PARD6B PARG PARP1 PARVA PCBP1 PCBP2 PCGF2 PCGF6 PCYOX1 PDCD2L PDCD4 PDCD7 PDHX PDIA3 PDIA5 PDIA6 PDP1 PEX14 PGD PGK1 PGM1 PHAX PHC3 PHF10 PHF6 PHGDH PI4K2A PICALM PIP4K2C PKM PKP4 PLD3 PLEKHO1 PLIN2 PLS3 PM20D2 PMPCA PNKP PNMA8A POGLUT3 POLD2 POLDIP3 POLM POLR1E POLR3C POLR3D POMK PPAT PPHLN1 PPM1F PPP1R7 PPP2R1A PPP2R1B PPP2R5C PPP2R5E PPP3CA PPP5C PRC1 PRCP PRIM1 PRIM2 PRKAR1A PRKAR2A PRKAR2B PRORP PRPF19 PRPF31 PRRC1 PSG1 PSIP1 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD12 PSMD4 PTBP1 PTBP2 PUF60 PURA PWP1 QRSL1 RAB11FIP2 RAD23A RAD23B RANGAP1 RAP1GDS1 RARS1 RARS2 RBFOX2 RBM17 RBM22 RBM23 RBM39 RBM42 RBM45 RBMS1 RBMX RCC1 RCN2 REPIN1 REXO4 RIC8A RING1 RIOX2 RNH1 RNPS1 RO60 RPL10 RPL10A RPL11 RPL12 RPL13 RPL22 RPL24 RPL3 RPL30 RPL4 RPL5 RPL6 RPL7 RPL8 RPL9 RPLP0 RPS2 RPS24 RPS3 RPS3A RPS4X RPS7 RPSA RPTOR RRP1 RRP1B RRP8 RRS1 RSRC2 RTCB RTN4 RUVBL1 RUVBL2 SAAL1 SAP30BP SARS2 SCAI SCLY SCP2 SCRIB SCRN1 SDE2 SEC62 SENP2 SEPTIN11 SEPTIN7 SERBP1 SERPINH1 SETD7 SF1 SF3A2 SF3A3 SF3B4 SFPQ SGSH SH3GLB2 SHMT2 SHOC2 SIN3A SLIT2 SMARCD1 SMARCD2 SMARCE1 SMPDL3B SNAP91 SNRNP70 SNW1 SNX4 SNX5 SNX6 SP1 SPAST SPATS2 SPATS2L SPOUT1 SQSTM1 SRF SRFBP1 SRP54 SRP68 SRP72 SRSF11 SRSF6 SRSF7 SSB ST13 STAU1 STAU2 STIP1 STK24 STK25 STK26 STK3 STK4 STOML2 SVOP SYAP1 SYNCRIP TAB1 TAB3 TADA2B TADA3 TAF15 TAF7 TARBP2 TBCE TBCEL TBL1XR1 TCP1 TCP11L1 TEDC1 TEDC2 TENT2 TERF1 TET2 TFDP1 TFG THRAP3 THUMPD1 TMCC3 TMEM30A TMPO TMX3 TOE1 TOM1 TOMM70 TOR1AIP1 TOR1AIP2 TP53 TPP1 TRAF4 TRAF7 TRAK1 TRAK2 TRIM11 TRIM27 TRIM28 TRIP12 TRIT1 TRMT10C TRMT5 TRMT6 TSG101 TSPYL1 TTC31 TTC4 TUBA1A TUBA1B TUBA1C TUBA4A TUBB TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBG1 TUFM TXNDC5 U2AF2 UBA1 UBA3 UBA5 UBC UBE2Q1 UBR7 UBXN6 UCHL5 UMPS UPF3B UQCRC1 USP14 UTP18 UTP3 VEZF1 VIM VIPAS39 VPS4A VPS4B VRK1 VRK2 VRK3 WARS1 WBP4 WDR55 WT1 WTAP XIAP XPO1 XRCC4 XRCC6 XRN2 YARS1 YBX1 YBX3 YES1 YJU2B YME1L1 YTHDF2 ZBTB14 ZC3H15 ZC3HAV1 ZCCHC3 ZKSCAN4 ZKSCAN8 ZNF124 ZNF207 ZNF277 ZNF385A ZNF397 ZNF436 ZNF460 ZNF48 ZNF622 ZNF70 ZNF703 ZNF768 ZNF787 ZNG1F ZNHIT2 ZPR1 ZRANB2 ZSCAN21	64 interacting genes: ANAPC11 ARID4A BRCA1 BTG2 CCNB1IP1 CCNF CDC25A CDC25C CDC34 CDC6 CDH1 CDK1 CDKN1A CDKN1B CDT1 CEBPA CSNK2B CUX1 EP300 FLNA FZR1 GADD45A GADD45B GADD45G H1-1 H1-5 HERC5 ITPR1 KAT5 KPNB1 MAP4 MEF2C MOK NACC1 OGT OTUD7B PBK PCNA PIN1 PKMYT1 PLK1 PRC1 PRKDC PTCH1 PTMA RALBP1 RB1 RUNX2 TGFBR2 TP53BP1 TP73 TSC1 TSPYL2 TULP3 UBE2D2 UBE2N UBE3C UBE3D UCHL3 USP39 WEE1 XIAP XRCC6 ZFAND5
Entrez ID		8473	891
HPRD ID		02222	00454
Ensembl ID		ENSG00000147162	ENSG00000134057
Uniprot IDs		O15294	P14635
PDB IDs		1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4CDR 4GYW 4GYY 4GZ3 4GZ5 4GZ6 4N39 4N3A 4N3B 4N3C 4XI9 4XIF 5BNW 5C1D 5HGV 5LVV 5LWV 5NPR 5NPS 5VIE 5VIF 6E37 6EOU 6IBO 6MA1 6MA2 6MA3 6MA4 6MA5 6Q4M 6TKA 7NTF 7YEA 7YEH 8CM9 8FE6 8FE7 8FUF	2B9R 2JGZ 4Y72 4YC3 5HQ0 5LQF 6GU2 6GU3 6GU4 7NJ0 8TAR 8TAU 9FH9
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleus RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process RNA Processing Macromolecule Metabolic Process Cytoplasm Ribonucleoprotein Complex Nucleoplasm Nucleic Acid Binding Cytosol MRNA Metabolic Process MRNA Processing RNA Splicing Extracellular Exosome MRNA Binding Protein Folding Nucleolus Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Translation Protein Binding Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of Translation Spliceosomal Complex Regulation Of MRNA Splicing, Via Spliceosome Cadherin Binding Post-transcriptional Regulation Of Gene Expression Protein-RNA Complex Assembly Nucleotide Binding Macromolecule Biosynthetic Process Cytosolic Ribosome Unfolded Protein Binding Protein-containing Complex Organization Protein Folding Chaperone ATP-dependent Protein Folding Chaperone Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Nuclear Speck Regulation Of Chromosome Organization Protein-containing Complex Biological_process RRNA Metabolic Process Cytoplasmic Stress Granule Protein-containing Complex Assembly ATP Binding Negative Regulation Of MRNA Metabolic Process	Regulation Of Cell Cycle Nucleoplasm Nucleus Regulation Of Protein Modification Process Intracellular Signal Transduction Negative Regulation Of Cell Cycle Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Negative Regulation Of Macromolecule Metabolic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of DNA Replication Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of Cell Cycle Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Cycle Phase Transition Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Positive Regulation Of DNA Replication Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Modification Process Signal Transduction In Response To DNA Damage Regulation Of Phosphorus Metabolic Process Negative Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Phosphorylation Positive Regulation Of DNA Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Stress Cell Division DNA Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of DNA Metabolic Process Cyclin Binding Regulation Of Kinase Activity DNA Damage Response Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process
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