OGT and SNAP91

Number of citations of the paper that reports this interaction (PMID 8063760)
7

Data Source:
HPRD (in vitro)

		OGT	SNAP91
Gene Name		O-linked N-acetylglucosamine (GlcNAc) transferase	synaptosomal-associated protein, 91kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytoplasm Mitochondrion Microtubule Organizing Center Cytosol Plasma Membrane MLL5-L Complex	Plasma Membrane Coated Pit Clathrin-coated Vesicle
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Enzyme Activator Activity Acetylglucosaminyltransferase Activity Protein N-acetylglucosaminyltransferase Activity Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific) Protein O-GlcNAc Transferase Activity	Protein Binding 1-phosphatidylinositol Binding Protein Kinase Binding Clathrin Binding
	Biological Process	Regulation Of Glycolytic Process Chromatin Organization Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Protein Ubiquitination Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction Positive Regulation Of Catalytic Activity Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone H3-K27 Methylation Cellular Response To Retinoic Acid Histone H3-K4 Trimethylation Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis	Synaptic Transmission Protein Transport Clathrin Coat Assembly Regulation Of Clathrin-mediated Endocytosis
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Bipolar disorder (mood-incongruent) ( 23092984)
Protein-Protein Interactions		18 interactors: CSNK2A1 GSK3B HCFC1 MAPT MGEA5 NUP62 NUP62CL PHC3 PSG1 SIN3A SNAP91 SP1 SRF TAB1 TET2 TRAK1 TRAK2 YES1	8 interactors: AP2A2 AP2B1 EPS15 NECAP1 OGT PLCG1 TRAF3IP1 TUBA1B
Entrez ID		8473	9892
HPRD ID		02222	06391
Ensembl ID		ENSG00000147162	ENSG00000065609
Uniprot IDs		O15294	B7Z2N2 O60641
PDB IDs		1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4GYW 4GYY 4GZ3 4GZ5 4GZ6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Growth Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Axon Extension Regulation Of Axon Extension Positive Regulation Of Growth Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Axonogenesis Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Localization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Protein O-linked Glycosylation Protein Transport Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Establishment Of Protein Localization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Rhythmic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Aging Regulation Of RNA Metabolic Process Developmental Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Complex Assembly Regulation Of Cell Growth Regulation Of Cell Size Megakaryocyte Differentiation Cell Morphogenesis Involved In Differentiation Trophectodermal Cell Differentiation Histone Modification Anatomical Structure Morphogenesis Regulation Of Gene Expression Cellular Protein Modification Process Positive Regulation Of Developmental Growth Regulation Of Axonogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Response To Organic Substance Negative Regulation Of Cellular Protein Metabolic Process Cellular Response To Organic Substance Neuron Projection Development Positive Regulation Of Protein Complex Assembly Glycoprotein Metabolic Process Negative Regulation Of Protein Metabolic Process Blastocyst Formation Regulation Of Metabolic Process In Utero Embryonic Development	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Regulation Of Immune System Process Regulation Of Defense Response To Virus By Virus Vesicle-mediated Transport Neurotrophin TRK Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin Signaling Pathway Intracellular Transport Regulation Of Signal Transduction Clathrin-mediated Endocytosis Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Signaling Transport Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Establishment Of Localization In Cell Axon Guidance Cell Morphogenesis Negative Regulation Of Signal Transduction Cell Projection Organization Negative Regulation Of Signaling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cellular Localization Ephrin Receptor Signaling Pathway Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Axonogenesis Response To Organic Substance Viral Process Protein Transport Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Establishment Of Protein Localization Chemotaxis Response To Growth Factor Movement Of Cell Or Subcellular Component Cytoskeleton-dependent Intracellular Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Response To External Stimulus
Tagcloud ?		acetylglucosamine aggregates autophagic autophagosome autophagosomes autophagy caenorhabditis defective elegans endosomes facilitates flux glcnac glcnacylated glcnacylation integrates lysosomes mammalian mediates mutating nutrient promotes regulates reveals snap snare starvation transferase
Tagcloud (Difference) ?		acetylglucosamine aggregates autophagic autophagosome autophagosomes autophagy caenorhabditis defective elegans endosomes facilitates flux glcnac glcnacylated glcnacylation integrates lysosomes mammalian mediates mutating nutrient promotes regulates reveals snap snare starvation transferase
Tagcloud (Intersection) ?