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CCNB1 and PKMYT1
Number of citations of the paper that reports this interaction (PubMedID
10373560
)
66
Data Source:
HPRD
(in vivo)
CCNB1
PKMYT1
Description
cyclin B1
protein kinase, membrane associated tyrosine/threonine 1
Image
GO Annotations
Cellular Component
Spindle Pole
Outer Kinetochore
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Matrix
Centrosome
Microtubule Organizing Center
Cytosol
Cytoskeleton
Membrane
Cyclin B1-CDK1 Complex
Golgi Membrane
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Molecular Function
Patched Binding
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Ubiquitin-like Protein Ligase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Metal Ion Binding
Protein Serine Kinase Activity
Biological Process
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Oocyte Maturation
In Utero Embryonic Development
Mitotic Spindle Organization
Mitotic Metaphase Chromosome Alignment
Spermatogenesis
Response To Xenobiotic Stimulus
Response To Mechanical Stimulus
Response To Toxic Substance
Negative Regulation Of Gene Expression
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of MRNA 3'-end Processing
Tissue Regeneration
Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle
Positive Regulation Of Mitotic Cell Cycle
Response To DDT
Positive Regulation Of Fibroblast Proliferation
Digestive Tract Development
Cell Division
Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Ventricular Cardiac Muscle Cell Development
Positive Regulation Of Cardiac Muscle Cell Proliferation
Regulation Of Chromosome Condensation
Protein-containing Complex Assembly
Cellular Response To Iron(III) Ion
Cellular Response To Fatty Acid
Cellular Response To Hypoxia
Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Regulation Of Mitotic Nuclear Division
Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
Meiotic Cell Cycle
Negative Regulation Of G2/MI Transition Of Meiotic Cell Cycle
Pathways
E2F-enabled inhibition of pre-replication complex formation
Polo-like kinase mediated events
Golgi Cisternae Pericentriolar Stack Reorganization
APC/C:Cdc20 mediated degradation of Cyclin B
Regulation of APC/C activators between G1/S and early anaphase
Phosphorylation of the APC/C
Phosphorylation of Emi1
Condensation of Prophase Chromosomes
MASTL Facilitates Mitotic Progression
Resolution of Sister Chromatid Cohesion
Condensation of Prometaphase Chromosomes
Regulation of PLK1 Activity at G2/M Transition
Activation of NIMA Kinases NEK9, NEK6, NEK7
Initiation of Nuclear Envelope (NE) Reformation
Nuclear Pore Complex (NPC) Disassembly
Depolymerization of the Nuclear Lamina
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Mitotic Prophase
Cyclin A/B1/B2 associated events during G2/M transition
G2/M DNA replication checkpoint
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
The role of GTSE1 in G2/M progression after G2 checkpoint
Transcriptional regulation by RUNX2
Nuclear events stimulated by ALK signaling in cancer
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Polo-like kinase mediated events
Cyclin A/B1/B2 associated events during G2/M transition
G2/M DNA replication checkpoint
Drugs
Fostamatinib
Diseases
GWAS
Metabolic syndrome (
20694148
)
Interacting Genes
64 interacting genes:
ANAPC11
ARID4A
BRCA1
BTG2
CCNB1IP1
CCNF
CDC25A
CDC25C
CDC34
CDC6
CDH1
CDK1
CDKN1A
CDKN1B
CDT1
CEBPA
CSNK2B
CUX1
EP300
FLNA
FZR1
GADD45A
GADD45B
GADD45G
H1-1
H1-5
HERC5
ITPR1
KAT5
KPNB1
MAP4
MEF2C
MOK
NACC1
OGT
OTUD7B
PBK
PCNA
PIN1
PKMYT1
PLK1
PRC1
PRKDC
PTCH1
PTMA
RALBP1
RB1
RUNX2
TGFBR2
TP53BP1
TP73
TSC1
TSPYL2
TULP3
UBE2D2
UBE2N
UBE3C
UBE3D
UCHL3
USP39
WEE1
XIAP
XRCC6
ZFAND5
24 interacting genes:
ABHD16A
BCL2
CCNB1
CD3E
CD79A
CDK1
CLDN8
ELOVL4
FATE1
LIME1
LRRC25
MAPK10
MAPK8
PIN1
PLK1
RETREG3
SLC10A1
SLC30A8
SLC61A1
SLC71A2
STEAP3
TMEM101
TMEM229B
TMX2
Entrez ID
891
9088
HPRD ID
00454
03920
Ensembl ID
ENSG00000134057
ENSG00000127564
Uniprot IDs
P14635
Q0IJ49
Q99640
PDB IDs
2B9R
2JGZ
4Y72
4YC3
5HQ0
5LQF
6GU2
6GU3
6GU4
7NJ0
8TAR
8TAU
9FH9
3P1A
5VCV
5VCW
5VCX
5VCY
5VCZ
5VD0
5VD1
5VD3
8D6C
8D6D
8D6E
8D6F
8WJY
8ZTX
8ZU2
8ZUD
8ZUL
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Cycle
Nucleoplasm
Nucleus
Regulation Of Protein Modification Process
Intracellular Signal Transduction
Negative Regulation Of Cell Cycle
Regulation Of Primary Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of DNA Metabolic Process
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Negative Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of DNA Replication
Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle G2/M Phase Transition
Negative Regulation Of Cell Cycle Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Cell Cycle Phase Transition
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Catalytic Activity
Positive Regulation Of DNA Replication
Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
Protein Modification Process
Signal Transduction In Response To DNA Damage
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Cell Cycle G2/M Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Phosphorylation
Positive Regulation Of DNA Metabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Cell Division
DNA Metabolic Process
Regulation Of Protein Kinase Activity
Negative Regulation Of DNA Metabolic Process
Cyclin Binding
Regulation Of Kinase Activity
DNA Damage Response
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Membrane
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cyclin B1-CDK1 Complex
Protein Localization To Site Of Double-strand Break
JUN Kinase Activity
Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport
B Cell Receptor Complex
Immune Response-regulating Signaling Pathway
Mitotic Cell Cycle Phase Transition
Antigen Receptor-mediated Signaling Pathway
B Cell Receptor Signaling Pathway
G2/M Transition Of Mitotic Cell Cycle
Cell Cycle Phase Transition
Cell Cycle G2/M Phase Transition
Ventricular Cardiac Muscle Cell Development
Mitotic Nuclear Membrane Disassembly
Striated Muscle Cell Development
Cell Cycle G1/S Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Membrane Disassembly
Nuclear Membrane Disassembly
MAP Kinase Activity
Muscle Cell Development
Immune Response-activating Cell Surface Receptor Signaling Pathway
Response To Toxic Substance
Regulation Of Sister Chromatid Segregation
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Outer Kinetochore
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Protein Localization To Chromosome
Peptidyl-threonine Phosphorylation
Microtubule Polymerization
Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site
Regulation Of Circadian Rhythm
Fc-epsilon Receptor Signaling Pathway
Lymphocyte Proliferation
Regulation Of Mitotic Cell Cycle
Regulation Of Mitotic Nuclear Division
Regulation Of Cell Cycle G2/M Phase Transition
Mononuclear Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Endoplasmic Reticulum
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Microtubule Cytoskeleton Organization Involved In Mitosis
Positive Regulation Of Chromosome Segregation
Regulation Of Chromosome Segregation
Cellular Response To Hypoxia
Response To Iron Ion
Positive Regulation Of Cell Cycle G2/M Phase Transition
Response To Light Stimulus
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