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CCNB1 and ZFAND5
Number of citations of the paper that reports this interaction (PubMedID
37214989
)
0
Data Source:
BioGRID
(pull down)
CCNB1
ZFAND5
Description
cyclin B1
zinc finger AN1-type containing 5
Image
GO Annotations
Cellular Component
Spindle Pole
Outer Kinetochore
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Matrix
Centrosome
Microtubule Organizing Center
Cytosol
Cytoskeleton
Membrane
Cyclin B1-CDK1 Complex
Cytoplasm
Molecular Function
Patched Binding
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Ubiquitin-like Protein Ligase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
DNA Binding
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Oocyte Maturation
In Utero Embryonic Development
Mitotic Spindle Organization
Mitotic Metaphase Chromosome Alignment
Spermatogenesis
Response To Xenobiotic Stimulus
Response To Mechanical Stimulus
Response To Toxic Substance
Negative Regulation Of Gene Expression
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of MRNA 3'-end Processing
Tissue Regeneration
Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle
Positive Regulation Of Mitotic Cell Cycle
Response To DDT
Positive Regulation Of Fibroblast Proliferation
Digestive Tract Development
Cell Division
Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Ventricular Cardiac Muscle Cell Development
Positive Regulation Of Cardiac Muscle Cell Proliferation
Regulation Of Chromosome Condensation
Protein-containing Complex Assembly
Cellular Response To Iron(III) Ion
Cellular Response To Fatty Acid
Cellular Response To Hypoxia
Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport
In Utero Embryonic Development
Vasculature Development
Respiratory System Process
Fibroblast Migration
Platelet-derived Growth Factor Receptor Signaling Pathway
Skeletal System Morphogenesis
Smooth Muscle Tissue Development
Face Development
Pathways
E2F-enabled inhibition of pre-replication complex formation
Polo-like kinase mediated events
Golgi Cisternae Pericentriolar Stack Reorganization
APC/C:Cdc20 mediated degradation of Cyclin B
Regulation of APC/C activators between G1/S and early anaphase
Phosphorylation of the APC/C
Phosphorylation of Emi1
Condensation of Prophase Chromosomes
MASTL Facilitates Mitotic Progression
Resolution of Sister Chromatid Cohesion
Condensation of Prometaphase Chromosomes
Regulation of PLK1 Activity at G2/M Transition
Activation of NIMA Kinases NEK9, NEK6, NEK7
Initiation of Nuclear Envelope (NE) Reformation
Nuclear Pore Complex (NPC) Disassembly
Depolymerization of the Nuclear Lamina
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Mitotic Prophase
Cyclin A/B1/B2 associated events during G2/M transition
G2/M DNA replication checkpoint
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
The role of GTSE1 in G2/M progression after G2 checkpoint
Transcriptional regulation by RUNX2
Nuclear events stimulated by ALK signaling in cancer
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Drugs
Diseases
GWAS
Sensorimotor dexterity (
31596458
)
Interacting Genes
64 interacting genes:
ANAPC11
ARID4A
BRCA1
BTG2
CCNB1IP1
CCNF
CDC25A
CDC25C
CDC34
CDC6
CDH1
CDK1
CDKN1A
CDKN1B
CDT1
CEBPA
CSNK2B
CUX1
EP300
FLNA
FZR1
GADD45A
GADD45B
GADD45G
H1-1
H1-5
HERC5
ITPR1
KAT5
KPNB1
MAP4
MEF2C
MOK
NACC1
OGT
OTUD7B
PBK
PCNA
PIN1
PKMYT1
PLK1
PRC1
PRKDC
PTCH1
PTMA
RALBP1
RB1
RUNX2
TGFBR2
TP53BP1
TP73
TSC1
TSPYL2
TULP3
UBE2D2
UBE2N
UBE3C
UBE3D
UCHL3
USP39
WEE1
XIAP
XRCC6
ZFAND5
14 interacting genes:
APP
CCNB1
IKBKG
LRRK2
MAP3K1
MFHAS1
PSMD6
PTTG1
RAD23B
RIPK1
SMURF1
TNFAIP3
TRAF6
UBC
Entrez ID
891
7763
HPRD ID
00454
05302
Ensembl ID
ENSG00000134057
ENSG00000107372
Uniprot IDs
P14635
O76080
PDB IDs
2B9R
2JGZ
4Y72
4YC3
5HQ0
5LQF
6GU2
6GU3
6GU4
7NJ0
8TAR
8TAU
9FH9
7QXW
Enriched GO Terms of Interacting Partners
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Regulation Of Cell Cycle
Nucleoplasm
Nucleus
Regulation Of Protein Modification Process
Intracellular Signal Transduction
Negative Regulation Of Cell Cycle
Regulation Of Primary Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of DNA Metabolic Process
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Negative Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of DNA Replication
Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle G2/M Phase Transition
Negative Regulation Of Cell Cycle Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Cell Cycle Phase Transition
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Catalytic Activity
Positive Regulation Of DNA Replication
Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
Protein Modification Process
Signal Transduction In Response To DNA Damage
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Cell Cycle G2/M Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Phosphorylation
Positive Regulation Of DNA Metabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Cell Division
DNA Metabolic Process
Regulation Of Protein Kinase Activity
Negative Regulation Of DNA Metabolic Process
Cyclin Binding
Regulation Of Kinase Activity
DNA Damage Response
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of JNK Cascade
Positive Regulation Of Defense Response
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Signal Transduction
Cytosol
Positive Regulation Of Immune System Process
Regulation Of JNK Cascade
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Negative Regulation Of Toll-like Receptor 2 Signaling Pathway
Regulation Of Protein Metabolic Process
Regulation Of Immune System Process
Protein Metabolic Process
Regulation Of Tumor Necrosis Factor Production
Regulation Of Proteolysis
Regulation Of Apoptotic Signaling Pathway
Cellular Response To Stress
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Inflammatory Response
Canonical NF-kappaB Signal Transduction
Positive Regulation Of Proteolysis
Positive Regulation Of MAPK Cascade
Response To Stress
Cellular Response To Manganese Ion
JUN Kinase Kinase Kinase Activity
Intracellular Signal Transduction
Regulation Of Defense Response
Intracellular Signaling Cassette
Negative Regulation Of Apoptotic Signaling Pathway
Signaling Adaptor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Cellular Response To Oxygen-containing Compound
Positive Regulation Of Catabolic Process
Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Intracellular Signal Transduction
Response To Manganese Ion
Regulation Of Immune Response
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Golgi-associated Vesicle
Cytoplasm
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Ubiquitin Protein Ligase Binding
Positive Regulation Of Tumor Necrosis Factor Production
Cellular Response To Reactive Oxygen Species
Cellular Response To Catecholamine Stimulus
Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production
Positive Regulation Of DNA-binding Transcription Factor Activity
Regulation Of Canonical NF-kappaB Signal Transduction
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