OGT and NUP62CL

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		OGT	NUP62CL
Gene Name		O-linked N-acetylglucosamine (GlcNAc) transferase	nucleoporin 62kDa C-terminal like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytoplasm Mitochondrion Microtubule Organizing Center Cytosol Plasma Membrane MLL5-L Complex	Nuclear Pore
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Enzyme Activator Activity Acetylglucosaminyltransferase Activity Protein N-acetylglucosaminyltransferase Activity Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific) Protein O-GlcNAc Transferase Activity	Structural Constituent Of Nuclear Pore
	Biological Process	Regulation Of Glycolytic Process Chromatin Organization Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Protein Ubiquitination Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction Positive Regulation Of Catalytic Activity Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone H3-K27 Methylation Cellular Response To Retinoic Acid Histone H3-K4 Trimethylation Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis	Protein Transport
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: CSNK2A1 GSK3B HCFC1 MAPT MGEA5 NUP62 NUP62CL PHC3 PSG1 SIN3A SNAP91 SP1 SRF TAB1 TET2 TRAK1 TRAK2 YES1	3 interactors: AGR2 APP OGT
Entrez ID		8473	54830
HPRD ID		02222	06527
Ensembl ID		ENSG00000147162	ENSG00000198088
Uniprot IDs		O15294	Q9H1M0
PDB IDs		1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4GYW 4GYY 4GZ3 4GZ5 4GZ6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Growth Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Axon Extension Regulation Of Axon Extension Positive Regulation Of Growth Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Axonogenesis Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Localization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Protein O-linked Glycosylation Protein Transport Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Establishment Of Protein Localization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Rhythmic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Aging Regulation Of RNA Metabolic Process Developmental Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Complex Assembly Regulation Of Cell Growth Regulation Of Cell Size Megakaryocyte Differentiation Cell Morphogenesis Involved In Differentiation Trophectodermal Cell Differentiation Histone Modification Anatomical Structure Morphogenesis Regulation Of Gene Expression Cellular Protein Modification Process Positive Regulation Of Developmental Growth Regulation Of Axonogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Response To Organic Substance Negative Regulation Of Cellular Protein Metabolic Process Cellular Response To Organic Substance Neuron Projection Development Positive Regulation Of Protein Complex Assembly Glycoprotein Metabolic Process Negative Regulation Of Protein Metabolic Process Blastocyst Formation Regulation Of Metabolic Process In Utero Embryonic Development	Mucus Secretion Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Lung Goblet Cell Differentiation Positive Regulation Of Proteolysis Collateral Sprouting Axon Midline Choice Point Recognition Lobar Bronchus Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Bronchus Development Positive Regulation Of Granulocyte Differentiation Neuron Remodeling Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Histone H3-K27 Methylation Cellular Chemical Homeostasis Histone H3-K4 Trimethylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Lung Secretory Cell Differentiation Regulation Of Histone H3-K27 Methylation Regulation Of Body Fluid Levels Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K4 Methylation Secretion Cellular Copper Ion Homeostasis Regulation Of Proteolysis Cellular Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Histone H3-K4 Methylation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Glycolytic Process Peptidyl-lysine Trimethylation Negative Regulation Of Cellular Protein Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Chemical Homeostasis Histone H3-K4 Methylation Negative Regulation Of Protein Metabolic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Rac Protein Signal Transduction RNA Polyadenylation Neuron Recognition Positive Regulation Of Histone Methylation Apoptotic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Tagcloud ?		acetylglucosamine aggregates autophagic autophagosome autophagosomes autophagy caenorhabditis defective elegans endosomes facilitates flux glcnac glcnacylated glcnacylation integrates lysosomes mammalian mediates mutating nutrient promotes regulates reveals snap snare starvation transferase
Tagcloud (Difference) ?		acetylglucosamine aggregates autophagic autophagosome autophagosomes autophagy caenorhabditis defective elegans endosomes facilitates flux glcnac glcnacylated glcnacylation integrates lysosomes mammalian mediates mutating nutrient promotes regulates reveals snap snare starvation transferase
Tagcloud (Intersection) ?