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AFAP1L2 and ACD
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
AFAP1L2
ACD
Gene Name
actin filament associated protein 1-like 2
adrenocortical dysplasia homolog (mouse)
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
SH3 Domain Binding
Protein Tyrosine Kinase Activator Activity
Signaling Adaptor Activity
SH2 Domain Binding
DNA Binding
Protein Binding
DNA Polymerase Binding
Biological Process
Inflammatory Response
Regulation Of Mitotic Cell Cycle
Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Protein Tyrosine Kinase Activity
Telomere Maintenance
Skeletal System Development
Urogenital System Development
Intracellular Protein Transport
Telomere Capping
Embryonic Limb Morphogenesis
Protection From Non-homologous End Joining At Telomere
Telomere Assembly
Negative Regulation Of Telomere Maintenance Via Telomerase
Segmentation
Positive Regulation Of Telomerase Activity
Positive Regulation Of Single-stranded Telomeric DNA Binding
Protein Localization To Chromosome, Telomeric Region
Pathways
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Drugs
Diseases
GWAS
Cognitive performance (
20125193
)
Protein-Protein Interactions
9 interactors:
ACD
APP
ATXN1L
POT1
RASA1
SRC
TERF1
TERF2
TINF2
59 interactors:
ACTB
ADPRH
AFAP1L2
AIPL1
ANKMY2
APOBEC3F
BAG3
CKB
CTTN
DBN1
DBNL
DCX
DPYSL3
EIF3G
EIF4B
ENO2
ENSA
FAM131B
FKBP6
GAPDH
HSP90AB1
IPO5
IVL
LASP1
LDHA
LGALSL
LLGL1
LRRC25
NCDN
NUDC
NUDCD2
PAGE2
PDLIM2
PEX5
PFKP
PGM2
POT1
RBKS
RECQL4
RGS3
RPSA
SBDS
STIP1
STUB1
SULT1C2
TAGLN
TBC1D10A
TBCD
TINF2
TOMM34
TRIM15
TRIM16
TUBB2A
TUBB4B
USP7
XRCC6
YWHAE
ZFP36L1
ZNF790
Entrez ID
84632
65057
HPRD ID
13902
12417
Ensembl ID
ENSG00000169129
ENSG00000102977
Uniprot IDs
F5GZE1
Q8N4X5
Q96AP0
PDB IDs
2COF
2I46
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of DNA Replication
Telomere Maintenance
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Metabolic Process
Telomere Assembly
Telomere Capping
Telomere Maintenance Via Telomere Lengthening
Regulation Of DNA Replication
Protein Localization To Chromosome, Telomeric Region
Positive Regulation Of DNA Metabolic Process
Regulation Of DNA Biosynthetic Process
Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance
Regulation Of Organelle Organization
Regulation Of Chromosome Organization
Regulation Of Telomerase Activity
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of DNA Biosynthetic Process
RNA-dependent DNA Replication
Negative Regulation Of Biosynthetic Process
Homeostatic Process
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Protein Localization To Chromosome
Positive Regulation Of Organelle Organization
Telomeric Loop Formation
Age-dependent Telomere Shortening
Telomere Maintenance Via Telomere Shortening
Protection From Non-homologous End Joining At Telomere
Regulation Of Cellular Component Organization
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Telomerase Activity
Replicative Cell Aging
Regulation Of Nuclear Cell Cycle DNA Replication
Negative Regulation Of Telomerase Activity
Chromosome Organization
Cellular Component Assembly
DNA Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of DNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Regulation Of Catalytic Activity
Negative Regulation Of Cell-matrix Adhesion
Positive Regulation Of Cellular Metabolic Process
Regulation Of Binding
Positive Regulation Of Catalytic Activity
DNA Replication
Organelle Organization
Protein Folding
Carbohydrate Catabolic Process
Substantia Nigra Development
Neural Nucleus Development
'de Novo' Posttranslational Protein Folding
'de Novo' Protein Folding
Nervous System Development
Catabolic Process
Cellular Component Assembly
Midbrain Development
Glycolytic Process
Multicellular Organismal Development
Negative Regulation Of Telomere Maintenance Via Telomerase
Generation Of Neurons
Telomere Assembly
Pyruvate Metabolic Process
Neurogenesis
Developmental Process
Negative Regulation Of Telomere Maintenance
Monosaccharide Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Brain Development
Cellular Metabolic Process
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Head Development
Glucose Metabolic Process
Neuron Projection Development
Neuron Projection Morphogenesis
Telomere Maintenance
Cell Differentiation
Neuron Differentiation
Regulation Of Protein Metabolic Process
System Development
DNA Duplex Unwinding
DNA Geometric Change
Regulation Of Telomere Maintenance
Cellular Process
Neuron Development
Adherens Junction Organization
Central Nervous System Development
Pathogenesis
Hexose Metabolic Process
Cellular Carbohydrate Metabolic Process
Negative Regulation Of DNA Metabolic Process
Protein Polymerization
Regulation Of Signaling
Innate Immune Response
DNA Metabolic Process
Tagcloud
?
acpra
apng1
arg52
betaherpesvirus
capsid
carboxy
carboxyl
ccd
corroborated
counterparts
cytomegalovirus
deleting
gal4
gammaherpesvirus
hcmv
his34
homologs
maturational
mcp
pap
proteinase
replace
scmv
simian
substituting
transporting
ul80
ul80a
ul86
Tagcloud (Difference)
?
acpra
apng1
arg52
betaherpesvirus
capsid
carboxy
carboxyl
ccd
corroborated
counterparts
cytomegalovirus
deleting
gal4
gammaherpesvirus
hcmv
his34
homologs
maturational
mcp
pap
proteinase
replace
scmv
simian
substituting
transporting
ul80
ul80a
ul86
Tagcloud (Intersection)
?