MAP1S and RASSF1

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology)
HPRD (in vivo, two hybrid, in vitro)

		MAP1S	RASSF1
Description		microtubule associated protein 1S	Ras association domain family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Microtubule Organizing Center Spindle Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Microtubule Cytoskeleton Dendrite Cell Projection Neuronal Cell Body Synapse Perinuclear Region Of Cytoplasm Mitotic Spindle Microtubule	Spindle Pole Nucleus Cytoplasm Centrosome Spindle Cytoskeleton Microtubule Microtubule Cytoskeleton
	Molecular Function	DNA Binding Actin Binding DNA Nuclease Activity Protein Binding Microtubule Binding Tubulin Binding Identical Protein Binding Beta-tubulin Binding Actin Filament Binding	Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Autophagy Apoptotic Process Mitotic Spindle Organization Nervous System Development Axonogenesis Brain Development Dendrite Development Regulation Of Microtubule Depolymerization Microtubule Anchoring At Centrosome Mitochondrion Transport Along Microtubule Neuron Projection Morphogenesis Metaphase Chromosome Alignment	DNA Damage Response Signal Transduction Ras Protein Signal Transduction Positive Regulation Of Protein Ubiquitination Protein Stabilization Regulation Of Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition
Pathways
Drugs
Diseases			Nasopharyngeal cancer Non-small cell lung cancer Bladder cancer
GWAS		Coronary artery disease ( 29212778 33020668) Height ( 28552196)	Basophil percentage of white cells ( 32888494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		15 interacting genes: ATM BPY2 BPY2C FILNC1 HDAC4 KCNJ6 LRPPRC MAP1LC3A NLGN3 PIN1 RASSF1 SLC2A4 SOCS3 SRPK2 VHL	68 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PRKDC RAF1 RASSF5 RELA RHOA RHOU SMARCA4 STK11 STK4 SUV39H1 SUV39H2 TEAD2 TERT TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA
Entrez ID		55201	11186
HPRD ID		10461	05470
Ensembl ID		ENSG00000130479	ENSG00000068028
Uniprot IDs		Q66K74	Q9NS23
PDB IDs			2KZU
Enriched GO Terms of Interacting Partners?		HECT Domain Binding Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Protein Stabilization Response To Decreased Oxygen Levels Response To Oxygen Levels Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Protein Stability Cellular Response To Hypoxia Negative Regulation Of Catabolic Process Negative Regulation Of Receptor Signaling Pathway Via STAT Peptidyl-serine Phosphorylation Cis-trans Isomerase Activity Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane	Regulation Of Cell Cycle Intracellular Signal Transduction Protein Kinase Activity Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Kinase Activity Regulation Of Intracellular Signal Transduction Regulation Of Cell Cycle Phase Transition Protein Serine Kinase Activity Response To UV Regulation Of Signal Transduction By P53 Class Mediator Signal Transduction Regulation Of Mitotic Cell Cycle Response To Radiation Cellular Response To Radiation Regulation Of Signaling Regulation Of Cell Communication Positive Regulation Of Macromolecule Metabolic Process Protein Serine/threonine Kinase Activity Regulation Of Signal Transduction Regulation Of Cell Population Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Protein Modification Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Programmed Cell Death Cellular Response To UV Regulation Of Macromolecule Metabolic Process Regulation Of Cellular Component Organization Regulation Of Apoptotic Process Programmed Cell Death Nucleotide Binding Cell Death Cellular Response To Light Stimulus Regulation Of Protein Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Protein Modification Process Response To Light Stimulus Apoptotic Process Apoptotic Signaling Pathway Cell Cycle Phase Transition Cellular Response To Stress Positive Regulation Of Cellular Component Organization Regulation Of Catalytic Activity ATP Binding Negative Regulation Of Signal Transduction Transferase Activity Regulation Of Protein Phosphorylation Mitotic Cell Cycle Phase Transition
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