MEGF10 and SHTN1

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		MEGF10	SHTN1
Description		multiple EGF like domains 10	shootin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Plasma Membrane Membrane Cell Projection	Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Microtubule Cytoskeleton Lamellipodium Filopodium Axon Growth Cone Cell Leading Edge Cell Projection Perikaryon Axonal Growth Cone Perinuclear Region Of Cytoplasm
	Molecular Function	Complement Component C1q Complex Binding Scavenger Receptor Activity Notch Binding	Protein Binding Kinesin Binding Identical Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Phagocytosis Cell Adhesion Muscle Organ Development Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Vesicle-mediated Transport Positive Regulation Of Cell-cell Adhesion Muscle Cell Proliferation Homotypic Cell-cell Adhesion Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Cell Development Myoblast Development Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Myoblast Migration Muscle Cell Development Apoptotic Process Involved In Development Positive Regulation Of Myoblast Proliferation	Substrate-dependent Cell Migration, Cell Extension Ras Protein Signal Transduction Axonogenesis Cdc42 Protein Signal Transduction Netrin-activated Signaling Pathway Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Cytoplasmic Actin-based Contraction Involved In Cell Motility Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport Regulation Of Establishment Of Cell Polarity Regulation Of Neuron Migration Positive Regulation Of Neuron Migration
Pathways			Recycling pathway of L1
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Appendicular lean mass ( 33097823) Bone mineral content ( 31790847) Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Hearing loss in Charcot-Marie-Tooth disease 1A ( 30958311) Initial pursuit acceleration ( 29064472) Response to antipsychotic treatment in schizophrenia ( 29503163)	Age at first sexual intercourse ( 34211149) Cortical surface area ( 32963231) Cortical volume ( 32963231) Lysophosphatidylethanolamine levels ( 31551469)
Interacting Genes		24 interacting genes: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 GULP1 HDAC4 ITSN2 MCF2L2 RANBP10 SART3 SCAPER SHANK3 SHTN1 SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1	20 interacting genes: BBOX1 DSCAM ESRRG EXOC6B FABP3 IGL IKBKG LNX1 LNX2 MEGF10 NEDD4 NME7 NRIP1 PCNT PRMT2 TFCP2 TNIP1 TP53BP2 WEE2-AS1 ZCCHC17
Entrez ID		84466	57698
HPRD ID		14384	11155
Ensembl ID		ENSG00000145794	ENSG00000187164
Uniprot IDs		Q96KG7	A0MZ66
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm
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