MEGF10 and TAOK2

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		MEGF10	TAOK2
Gene Name		multiple EGF-like-domains 10	TAO kinase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Phagocytic Cup Integral Component Of Membrane Basolateral Plasma Membrane Cell Projection	Nucleus Nucleolus Cytoplasm Cytoskeleton Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle Dendrite Cytoplasmic Vesicle Membrane Receptor Complex
	Molecular Function		Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity ATP Binding Mitogen-activated Protein Kinase Kinase Binding
	Biological Process	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Homotypic Cell-cell Adhesion Recognition Of Apoptotic Cell Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Muscle Cell Development	Activation Of MAPKK Activity Regulation Of Cell Growth Protein Phosphorylation Protein Targeting To Membrane Apoptotic Process Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization G2 DNA Damage Checkpoint Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of JNK Cascade Focal Adhesion Assembly Stress-activated MAPK Cascade
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)
Protein-Protein Interactions		22 interactors: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 HDAC4 ITSN2 KIAA1598 MCF2L2 RANBP10 SART3 SCAPER SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1	9 interactors: ELK1 KLHL12 MAP2K3 MAP2K6 MEGF10 RCHY1 TUBA1A TUBA4A TUBB
Entrez ID		84466	9344
HPRD ID		14384	18147
Ensembl ID		ENSG00000145794	ENSG00000149930
Uniprot IDs		Q96KG7	Q9UL54
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cellular Component Assembly Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome Positive Regulation Of Histone Deubiquitination Mitochondrial Alanyl-tRNA Aminoacylation RNA Splicing, Via Transesterification Reactions Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Cellular Macromolecular Complex Assembly Regulation Of Generation Of Precursor Metabolites And Energy Cis Assembly Of Pre-catalytic Spliceosome	Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Protein Polymerization Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade G2/M Transition Of Mitotic Cell Cycle Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response MAPK Cascade Regulation Of Innate Immune Response Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Response To Interleukin-4 Signal Transduction By Phosphorylation Innate Immune Response Response To Interleukin-4 Cardiac Muscle Contraction 'de Novo' Posttranslational Protein Folding Cellular Protein Complex Assembly 'de Novo' Protein Folding Heart Contraction Protein Complex Assembly Cell Cycle Process Skeletal Muscle Satellite Cell Proliferation Striated Muscle Contraction Microtubule Cytoskeleton Organization Immune Response-regulating Signaling Pathway Cellular Response To Testosterone Stimulus Skeletal Muscle Cell Proliferation Skeletal Muscle Satellite Cell Activation Immune Response Defense Response Cell Cycle Cellular Response To Sorbitol Cytoskeleton-dependent Intracellular Transport Activation Of MAPK Activity Cellular Macromolecular Complex Assembly Positive Regulation Of Immune Response
Tagcloud ?		adhere adopt ap2 ap50 associating autoimmunity ced cerebellum clathrin clearing coated colocalized corpses deeper dishes elucidating engulfment flat immunoblot irregular mirrored mosaic nematode ortholog pits stellate ubiquitinated unusually vacuoles
Tagcloud (Difference) ?		adhere adopt ap2 ap50 associating autoimmunity ced cerebellum clathrin clearing coated colocalized corpses deeper dishes elucidating engulfment flat immunoblot irregular mirrored mosaic nematode ortholog pits stellate ubiquitinated unusually vacuoles
Tagcloud (Intersection) ?