MEGF10 and VWA8

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		MEGF10	VWA8
Description		multiple EGF like domains 10	von Willebrand factor A domain containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Plasma Membrane Membrane Cell Projection	Cytoplasm Mitochondrion Peroxisome
	Molecular Function	Complement Component C1q Complex Binding Scavenger Receptor Activity Notch Binding	Nucleotide Binding Protein Binding ATP Binding ATP Hydrolysis Activity
	Biological Process	Phagocytosis Cell Adhesion Muscle Organ Development Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Vesicle-mediated Transport Positive Regulation Of Cell-cell Adhesion Muscle Cell Proliferation Homotypic Cell-cell Adhesion Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Cell Development Myoblast Development Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Myoblast Migration Muscle Cell Development Apoptotic Process Involved In Development Positive Regulation Of Myoblast Proliferation
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Appendicular lean mass ( 33097823) Bone mineral content ( 31790847) Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Hearing loss in Charcot-Marie-Tooth disease 1A ( 30958311) Initial pursuit acceleration ( 29064472) Response to antipsychotic treatment in schizophrenia ( 29503163)	Heel bone mineral density x serum urate levels interaction ( 34046847) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Local histogram emphysema pattern ( 25006744) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Tuberculosis ( 24057671)
Interacting Genes		24 interacting genes: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 GULP1 HDAC4 ITSN2 MCF2L2 RANBP10 SART3 SCAPER SHANK3 SHTN1 SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1	1 interacting genes: MEGF10
Entrez ID		84466	23078
HPRD ID		14384	17194
Ensembl ID		ENSG00000145794	ENSG00000102763
Uniprot IDs		Q96KG7	A3KMH1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm	Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Complement Component C1q Complex Binding Myoblast Development Skeletal Muscle Satellite Cell Activation Skeletal Muscle Cell Proliferation Phagocytosis, Recognition Myoblast Migration Positive Regulation Of Myoblast Proliferation Regulation Of Skeletal Muscle Tissue Development Regulation Of Myoblast Proliferation Phagocytic Cup Muscle Cell Migration Scavenger Receptor Activity Notch Binding Apoptotic Cell Clearance Phagocytosis, Engulfment Apoptotic Process Involved In Development Muscle Cell Proliferation Regulation Of Striated Muscle Tissue Development Regulation Of Muscle Organ Development Membrane Invagination Skeletal Muscle Cell Differentiation Homotypic Cell-cell Adhesion Phagocytosis Muscle Cell Development Cell Recognition Muscle Organ Development Muscle Structure Development Regulation Of Muscle Cell Differentiation Positive Regulation Of Cell-cell Adhesion
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