SHTN1 and ZCCHC17

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		SHTN1	ZCCHC17
Description		shootin 1	zinc finger CCHC-type containing 17
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Microtubule Cytoskeleton Lamellipodium Filopodium Axon Growth Cone Cell Leading Edge Cell Projection Perikaryon Axonal Growth Cone Perinuclear Region Of Cytoplasm	Nucleus Nucleolus Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex
	Molecular Function	Protein Binding Kinesin Binding Identical Protein Binding Cadherin Binding Actin Filament Binding	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Substrate-dependent Cell Migration, Cell Extension Ras Protein Signal Transduction Axonogenesis Cdc42 Protein Signal Transduction Netrin-activated Signaling Pathway Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Cytoplasmic Actin-based Contraction Involved In Cell Motility Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport Regulation Of Establishment Of Cell Polarity Regulation Of Neuron Migration Positive Regulation Of Neuron Migration	RNA Stabilization
Pathways		Recycling pathway of L1
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Cortical surface area ( 32963231) Cortical volume ( 32963231) Lysophosphatidylethanolamine levels ( 31551469)	Alcohol dependence ( 23455491) Body mass index ( 26426971 29615537)
Interacting Genes		20 interacting genes: BBOX1 DSCAM ESRRG EXOC6B FABP3 IGL IKBKG LNX1 LNX2 MEGF10 NEDD4 NME7 NRIP1 PCNT PRMT2 TFCP2 TNIP1 TP53BP2 WEE2-AS1 ZCCHC17	16 interacting genes: AP1M1 APP CACNA1A EHHADH KDM1A LXN NTAQ1 PNN RNF4 SDCBP SDCBP2 SHTN1 SRPK2 SUV39H1 ZDHHC17 ZNF16
Entrez ID		57698	51538
HPRD ID		11155	15189
Ensembl ID		ENSG00000187164	ENSG00000121766
Uniprot IDs		A0MZ66	A0A087WXF8 A0A087WXU5 A0A087WYF0 A0A087WYV3 A0A0D9SEW3 B4DYA9 Q9NP64
PDB IDs			2CQO
Enriched GO Terms of Interacting Partners?			Substrate-dependent Cell Migration, Cell Extension
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