MEGF10 and SNRNP200

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		MEGF10	SNRNP200
Gene Name		multiple EGF-like-domains 10	small nuclear ribonucleoprotein 200kDa (U5)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Phagocytic Cup Integral Component Of Membrane Basolateral Plasma Membrane Cell Projection	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Catalytic Step 2 Spliceosome
	Molecular Function		ATP-dependent RNA Helicase Activity Protein Binding ATP Binding ATP-dependent Helicase Activity Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Homotypic Cell-cell Adhesion Recognition Of Apoptotic Cell Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Muscle Cell Development	Cis Assembly Of Pre-catalytic Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)
Protein-Protein Interactions		22 interactors: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 HDAC4 ITSN2 KIAA1598 MCF2L2 RANBP10 SART3 SCAPER SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1	19 interactors: APC BARD1 BRCA1 CHMP1B ECT2 ERG GRB2 LSM8 MEGF10 PIN1 PRPF8 RNF113A SART1 SF3B2 SMNDC1 SNRNP40 USP19 YWHAB YWHAG
Entrez ID		84466	23020
HPRD ID		14384	03391
Ensembl ID		ENSG00000145794	ENSG00000144028
Uniprot IDs		Q96KG7	O75643
PDB IDs			2Q0Z 4F91 4F92 4F93 4KIT
Enriched GO Terms of Interacting Partners?		Organelle Organization Cellular Component Assembly Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome Positive Regulation Of Histone Deubiquitination Mitochondrial Alanyl-tRNA Aminoacylation RNA Splicing, Via Transesterification Reactions Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Cellular Macromolecular Complex Assembly Regulation Of Generation Of Precursor Metabolites And Energy Cis Assembly Of Pre-catalytic Spliceosome	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Organelle Organization RNA Splicing Regulation Of Cell Cycle MRNA Processing Regulation Of Cell Cycle Process MRNA Metabolic Process Cell Cycle RNA Processing Regulation Of Microtubule Cytoskeleton Organization Apoptotic Process Apoptotic Signaling Pathway Programmed Cell Death Cell Cycle Process Regulation Of Microtubule-based Process Cell Death Death Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Protein K6-linked Ubiquitination Regulation Of Cytoskeleton Organization Regulation Of Phosphorylation Regulation Of Cell Division Regulation Of Cellular Component Organization Cytokinesis Positive Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell Cycle Arrest Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Regulation Of Intracellular Transport Cellular Component Assembly Ribonucleoprotein Complex Assembly Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Cellular Response To Organonitrogen Compound Spliceosomal SnRNP Assembly Regulation Of Apoptotic Process Regulation Of Centrosome Duplication
Tagcloud ?		adhere adopt ap2 ap50 associating autoimmunity ced cerebellum clathrin clearing coated colocalized corpses deeper dishes elucidating engulfment flat immunoblot irregular mirrored mosaic nematode ortholog pits stellate ubiquitinated unusually vacuoles
Tagcloud (Difference) ?		adhere adopt ap2 ap50 associating autoimmunity ced cerebellum clathrin clearing coated colocalized corpses deeper dishes elucidating engulfment flat immunoblot irregular mirrored mosaic nematode ortholog pits stellate ubiquitinated unusually vacuoles
Tagcloud (Intersection) ?