SHTN1 and IGL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SHTN1	IGL
Description		shootin 1	immunoglobulin lambda locus
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Microtubule Cytoskeleton Lamellipodium Filopodium Axon Growth Cone Cell Leading Edge Cell Projection Perikaryon Axonal Growth Cone Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Kinesin Binding Identical Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Substrate-dependent Cell Migration, Cell Extension Ras Protein Signal Transduction Axonogenesis Cdc42 Protein Signal Transduction Netrin-activated Signaling Pathway Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Cytoplasmic Actin-based Contraction Involved In Cell Motility Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport Regulation Of Establishment Of Cell Polarity Regulation Of Neuron Migration Positive Regulation Of Neuron Migration
Pathways		Recycling pathway of L1
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Cortical surface area ( 32963231) Cortical volume ( 32963231) Lysophosphatidylethanolamine levels ( 31551469)
Interacting Genes		20 interacting genes: BBOX1 DSCAM ESRRG EXOC6B FABP3 IGL IKBKG LNX1 LNX2 MEGF10 NEDD4 NME7 NRIP1 PCNT PRMT2 TFCP2 TNIP1 TP53BP2 WEE2-AS1 ZCCHC17	3 interacting genes: SGTA SHTN1 UBQLN1
Entrez ID		57698	3535
HPRD ID		11155	13731
Ensembl ID		ENSG00000187164
Uniprot IDs		A0MZ66
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport TRC Complex Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Cdc42 Protein Signal Transduction BAT3 Complex Binding Cytoplasmic Actin-based Contraction Involved In Cell Motility Identical Protein Binding Negative Regulation Of ERAD Pathway Regulation Of Protein Catabolic Process Regulation Of Proteolysis Netrin-activated Signaling Pathway Substrate-dependent Cell Migration, Cell Extension Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Toll-like Receptor 3 Signaling Pathway Proteasomal Protein Catabolic Process Aggrephagy Positive Regulation Of Neuron Migration Regulation Of Cellular Response To Stress Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Catabolic Process Protein Catabolic Process Regulation Of Establishment Of Cell Polarity Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Transporter Activity Axonal Growth Cone Regulation Of Establishment Or Maintenance Of Cell Polarity Perinuclear Region Of Cytoplasm Protein Targeting To ER Protein Insertion Into ER Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Aggresome Positive Regulation Of Protein Metabolic Process Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Axon Extension Microtubule Associated Complex Actin-mediated Cell Contraction
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