SHTN1 and EXOC6B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SHTN1	EXOC6B
Description		shootin 1	exocyst complex component 6B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Microtubule Cytoskeleton Lamellipodium Filopodium Axon Growth Cone Cell Leading Edge Cell Projection Perikaryon Axonal Growth Cone Perinuclear Region Of Cytoplasm	Exocyst Plasma Membrane
	Molecular Function	Protein Binding Kinesin Binding Identical Protein Binding Cadherin Binding Actin Filament Binding	Protein Binding
	Biological Process	Substrate-dependent Cell Migration, Cell Extension Ras Protein Signal Transduction Axonogenesis Cdc42 Protein Signal Transduction Netrin-activated Signaling Pathway Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Cytoplasmic Actin-based Contraction Involved In Cell Motility Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport Regulation Of Establishment Of Cell Polarity Regulation Of Neuron Migration Positive Regulation Of Neuron Migration	Mitotic Cytokinesis Intracellular Protein Transport Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport Membrane Fission Vesicle Tethering Involved In Exocytosis
Pathways		Recycling pathway of L1
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Cortical surface area ( 32963231) Cortical volume ( 32963231) Lysophosphatidylethanolamine levels ( 31551469)	Appendicular lean mass ( 33097823) Diastolic blood pressure ( 27841878 30224653) Height ( 31562340) Malaria ( 31844061) Serum metabolite levels ( 33031748) Severe autoimmune type 2 diabetes ( 34737425) Systolic blood pressure ( 27841878)
Interacting Genes		20 interacting genes: BBOX1 DSCAM ESRRG EXOC6B FABP3 IGL IKBKG LNX1 LNX2 MEGF10 NEDD4 NME7 NRIP1 PCNT PRMT2 TFCP2 TNIP1 TP53BP2 WEE2-AS1 ZCCHC17	3 interacting genes: MTERF1 RALA SHTN1
Entrez ID		57698	23233
HPRD ID		11155	19418
Ensembl ID		ENSG00000187164	ENSG00000144036
Uniprot IDs		A0MZ66	A0A0U1RRB6 Q9Y2D4
PDB IDs
Enriched GO Terms of Interacting Partners?			Ras Protein Signal Transduction Glucosidase Activity Glc3Man9GlcNAc2 Oligosaccharide Glucosidase Activity Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport Edg-2 Lysophosphatidic Acid Receptor Binding Termination Of Mitochondrial Transcription Cdc42 Protein Signal Transduction Intracellular Signaling Cassette NF-kappaB Complex Cytoplasmic Actin-based Contraction Involved In Cell Motility Small GTPase-mediated Signal Transduction Membrane Raft Localization DNA Geometric Change Netrin-activated Signaling Pathway
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