SHTN1 and FABP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SHTN1	FABP3
Description		shootin 1	fatty acid binding protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Microtubule Cytoskeleton Lamellipodium Filopodium Axon Growth Cone Cell Leading Edge Cell Projection Perikaryon Axonal Growth Cone Perinuclear Region Of Cytoplasm	Extracellular Space Nucleus Cytoplasm Cytosol Sarcoplasm Extracellular Exosome
	Molecular Function	Protein Binding Kinesin Binding Identical Protein Binding Cadherin Binding Actin Filament Binding	Long-chain Fatty Acid Transmembrane Transporter Activity Fatty Acid Binding Protein Binding Cytoskeletal Protein Binding Lipid Binding Long-chain Fatty Acid Binding Icosatetraenoic Acid Binding Oleic Acid Binding
	Biological Process	Substrate-dependent Cell Migration, Cell Extension Ras Protein Signal Transduction Axonogenesis Cdc42 Protein Signal Transduction Netrin-activated Signaling Pathway Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Cytoplasmic Actin-based Contraction Involved In Cell Motility Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport Regulation Of Establishment Of Cell Polarity Regulation Of Neuron Migration Positive Regulation Of Neuron Migration	Fatty Acid Metabolic Process Negative Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Long-chain Fatty Acid Transport Intracellular Lipid Transport Response To Insulin Cholesterol Homeostasis Regulation Of Fatty Acid Oxidation Brown Fat Cell Differentiation Phospholipid Homeostasis Response To Fatty Acid Positive Regulation Of Phospholipid Biosynthetic Process Positive Regulation Of Long-chain Fatty Acid Import Into Cell Regulation Of Phosphatidylcholine Biosynthetic Process
Pathways		Recycling pathway of L1	Triglyceride catabolism
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Cortical surface area ( 32963231) Cortical volume ( 32963231) Lysophosphatidylethanolamine levels ( 31551469)	Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		20 interacting genes: BBOX1 DSCAM ESRRG EXOC6B FABP3 IGL IKBKG LNX1 LNX2 MEGF10 NEDD4 NME7 NRIP1 PCNT PRMT2 TFCP2 TNIP1 TP53BP2 WEE2-AS1 ZCCHC17	4 interacting genes: NUP62 SHTN1 TNNI3K VPS28
Entrez ID		57698	2170
HPRD ID		11155	00613
Ensembl ID		ENSG00000187164	ENSG00000121769
Uniprot IDs		A0MZ66	A0A384MDY5 P05413
PDB IDs			1G5W 1HMR 1HMS 1HMT 2HMB 3RSW 3WBG 3WVM 3WXQ 4TJZ 4TKB 4TKH 4TKJ 4WBK 5B27 5B28 5B29 5CE4 5HZ9 6AQ1 7EGO 7EUV 7EUW 7FBF 7FBM 7FBN 7FC4 7FCG 7FCX 7FD7 7FDT 7FDU 7FDX 7FEK 7FEU 7FEZ 7FF6 7FFK 7FFX 7FG1 7FG5 7FZQ 7V2G 7V5U 7VB1 7WCI 7WD6 7WDJ 7WE5 7WF0 7WJ1 7WKB 7WKG 7WOM 7WPG 7WPU 7WPW 7WQ7 7X48 7X4J 7X50 7XBC 7XHM 7XHU 8GEW
Enriched GO Terms of Interacting Partners?			Ubiquitin Binding Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport PTB Domain Binding Bundle Of His Cell To Purkinje Myocyte Communication Positive Regulation Of Ubiquitin-dependent Endocytosis Cdc42 Protein Signal Transduction Positive Regulation Of Cellular Component Organization Nuclear Pore Central Transport Channel Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Protein Localization To Centrosome Mitotic Centrosome Separation Peptidyl-serine Autophosphorylation Cytoplasmic Actin-based Contraction Involved In Cell Motility Netrin-activated Signaling Pathway Establishment Of Protein Localization To Organelle Substrate-dependent Cell Migration, Cell Extension Positive Regulation Of Centriole Replication ESCRT I Complex Centrosome Separation Regulation Of Protein Localization To Centrosome Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Positive Regulation Of Neuron Migration Positive Regulation Of Protein Localization Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
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