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WDR83 and TOE1
Number of citations of the paper that reports this interaction (PMID
22365833
)
24
Data Source:
BioGRID
(two hybrid)
WDR83
TOE1
Gene Name
WD repeat domain 83
target of EGR1, member 1 (nuclear)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Spliceosomal Complex
Cytoplasm
Catalytic Step 2 Spliceosome
Nucleus
Nucleoplasm
Nucleolus
Nuclear Speck
Molecular Function
Protein Binding
Nucleic Acid Binding
Protein Binding
Metal Ion Binding
Biological Process
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
17 interactors:
AQR
BAG2
CRB3
EGLN3
GNB2L1
GPKOW
HNRNPH2
HSPB1
KDM1A
KEAP1
LSM3
PARD6A
PARD6B
PCBP2
SAP30BP
SF1
TOE1
25 interactors:
ABCF3
AGGF1
AP2A1
APLP1
CA12
HNRNPF
IK
IL7R
LSM4
PPP1CA
PRCC
RAB40C
RBM39
RBM8A
RPS3A
SF3B2
SF3B3
SH3GL3
SQSTM1
SRSF6
SUMO1
U2AF1
UNC13B
WDR77
WDR83
Entrez ID
84292
114034
HPRD ID
14730
18212
Ensembl ID
ENSG00000123154
ENSG00000132773
Uniprot IDs
Q9BRX9
B4DEM6
Q96GM8
PDB IDs
2FC6
Enriched GO Terms of Interacting Partners
?
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Splicing
Tight Junction Assembly
MRNA Processing
Apical Junction Assembly
MRNA Metabolic Process
RNA Processing
Cell-cell Junction Assembly
Gene Expression
Negative Regulation Of Oxidative Stress-induced Cell Death
Regulation Of Intrinsic Apoptotic Signaling Pathway
Cell Junction Assembly
Cell-cell Junction Organization
Regulation Of Cellular Response To Oxidative Stress
RNA Metabolic Process
Regulation Of Primitive Erythrocyte Differentiation
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of CAMP Catabolic Process
Heterocycle Metabolic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hydrogen Peroxide-induced Neuron Death
Zymogen Activation
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Cell Death
Primary Sex Determination
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Proteasomal Ubiquitin-independent Protein Catabolic Process
Regulation Of Embryonic Development
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway
MRNA 3'-splice Site Recognition
Positive Regulation Of Endopeptidase Activity
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Female Gonad Development
Nitrogen Compound Metabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Peptidase Activity
Negative Regulation Of Oxidative Stress-induced Neuron Death
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Histone H3-K4 Methylation
MRNA Metabolic Process
RNA Processing
MRNA Processing
RNA Splicing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA 3'-end Processing
RNA 3'-end Processing
RNA Metabolic Process
Termination Of RNA Polymerase II Transcription
Gene Expression
Nucleobase-containing Compound Metabolic Process
MRNA Export From Nucleus
DNA-templated Transcription, Termination
RNA Export From Nucleus
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Nuclear Export
MRNA Transport
Nitrogen Compound Metabolic Process
RNA Transport
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Cellular Localization
Nuclear-transcribed MRNA Catabolic Process
RNA Localization
MRNA Catabolic Process
Cytoplasmic Transport
Establishment Of Localization In Cell
Intracellular Transport
RNA Catabolic Process
Positive Regulation Of Synaptic Vesicle Priming
Positive Regulation Of Synaptic Vesicle Exocytosis
Interleukin-7-mediated Signaling Pathway
Regulation Of MRNA Splicing, Via Spliceosome
Nucleocytoplasmic Transport
Cellular Metabolic Process
Nuclear Transport
Negative Regulation Of Hyaluronan Biosynthetic Process
Cellular Response To Norepinephrine Stimulus
Regulation Of Epithelial Cell Proliferation
Regulation Of MRNA Processing
PML Body Organization
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Positive Regulation Of Inhibitory Postsynaptic Membrane Potential
Negative Regulation Of T Cell Mediated Cytotoxicity
Cellular Process
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