WDR83

Description		WD repeat domain 83
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytoplasm Lysosome Endosome Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia Neural Tube Closure MRNA Processing RNA Splicing Response To Wounding Response To Lipopolysaccharide Regulation Of Canonical NF-kappaB Signal Transduction Placenta Blood Vessel Development Inflammatory Response To Wounding
Pathways		MAP2K and MAPK activation
Drugs
Diseases
GWAS
Interacting Genes		36 interacting genes: BAG2 BCAS2 BCL6 CRB3 CRK CRYAA EGLN3 EXOSC1 FAM124B FRS3 GNE GPKOW GTSE1 HNRNPH2 HOXA1 HSPB1 KCTD9 KDM1A KEAP1 LONRF1 LSM3 NOXA1 PARD6A PARD6B PCBP2 PRKAB2 RACK1 SAP30BP SF1 SRSF8 TLX3 TOE1 VAC14 WBP4 ZC3H7A ZNF76
Entrez ID		84292
HPRD ID		14730
Ensembl ID		ENSG00000123154
Uniprot IDs		Q9BRX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Identical Protein Binding RNA Binding Nucleic Acid Binding Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Processing PAR Polarity Complex RNA Splicing, Via Transesterification Reactions RNA Splicing Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Binding Establishment Or Maintenance Of Apical/basal Cell Polarity MRNA Metabolic Process MRNA Processing Establishment Or Maintenance Of Cell Polarity RNA Metabolic Process MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Precatalytic Spliceosome
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