WDR83 and BAG2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		WDR83	BAG2
Description		WD repeat domain 83	BAG cochaperone 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytoplasm Lysosome Endosome Membrane Catalytic Step 2 Spliceosome	Cytosol Microtubule Axon Dendrite Protein Folding Chaperone Complex Dendritic Microtubule
	Molecular Function	Protein Binding	Adenyl-nucleotide Exchange Factor Activity Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Transmembrane Transporter Binding Tau Protein Binding Protein-folding Chaperone Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia Neural Tube Closure MRNA Processing RNA Splicing Response To Wounding Response To Lipopolysaccharide Regulation Of Canonical NF-kappaB Signal Transduction Placenta Blood Vessel Development Inflammatory Response To Wounding	Protein Folding Positive Regulation Of Protein Processing Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Protein Stabilization Positive Regulation Of Proteasomal Protein Catabolic Process
Pathways		MAP2K and MAPK activation	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS
Interacting Genes		36 interacting genes: BAG2 BCAS2 BCL6 CRB3 CRK CRYAA EGLN3 EXOSC1 FAM124B FRS3 GNE GPKOW GTSE1 HNRNPH2 HOXA1 HSPB1 KCTD9 KDM1A KEAP1 LONRF1 LSM3 NOXA1 PARD6A PARD6B PCBP2 PRKAB2 RACK1 SAP30BP SF1 SRSF8 TLX3 TOE1 VAC14 WBP4 ZC3H7A ZNF76	17 interacting genes: CCAR2 DAPK1 DISC1 DNAJC6 HSPA1A HSPA4 HSPA8 LRRK1 LRRK2 MAPKAPK2 MFHAS1 NOTCH3 PINK1 PPIH SLU7 WDR77 WDR83
Entrez ID		84292	9532
HPRD ID		14730	04859
Ensembl ID		ENSG00000123154	ENSG00000112208
Uniprot IDs		Q9BRX9	O95816
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Identical Protein Binding RNA Binding Nucleic Acid Binding Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Processing PAR Polarity Complex RNA Splicing, Via Transesterification Reactions RNA Splicing Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Binding Establishment Or Maintenance Of Apical/basal Cell Polarity MRNA Metabolic Process MRNA Processing Establishment Or Maintenance Of Cell Polarity RNA Metabolic Process MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Precatalytic Spliceosome	C3HC4-type RING Finger Domain Binding Cytoplasm Negative Regulation Of Intrinsic Apoptotic Signaling Pathway ATP-dependent Protein Folding Chaperone Nucleotide Binding ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Clathrin Coat Disassembly Positive Regulation Of Wnt Signaling Pathway Regulation Of Synaptic Vesicle Transport ATP Binding Protein Serine Kinase Activity Regulation Of Signal Transduction Regulation Of Protein Stability Protein-containing Complex Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis MRNA Metabolic Process Spliceosomal Complex RNA Splicing Response To Stress Protein Serine/threonine Kinase Activity Regulation Of Intrinsic Apoptotic Signaling Pathway Heat Shock Protein Binding MRNA Splicing, Via Spliceosome Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Oxidative Stress Protein Folding Regulation Of Protein-containing Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing Cellular Response To Stress Negative Regulation Of Autophagosome Assembly Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Response To Unfolded Protein Protein Kinase Activity Adenyl-nucleotide Exchange Factor Activity Mitochondrion Organization Cellular Response To Chemical Stress Regulation Of Cellular Response To Stress Intracellular Signal Transduction Syntaxin-1 Binding Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Cytosol Calcium/calmodulin-dependent Protein Kinase Activity Ubiquitin Protein Ligase Binding
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