WDR83 and GTSE1

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		WDR83	GTSE1
Description		WD repeat domain 83	G2 and S-phase expressed 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytoplasm Lysosome Endosome Membrane Catalytic Step 2 Spliceosome	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia Neural Tube Closure MRNA Processing RNA Splicing Response To Wounding Response To Lipopolysaccharide Regulation Of Canonical NF-kappaB Signal Transduction Placenta Blood Vessel Development Inflammatory Response To Wounding	Microtubule-based Process DNA Damage Response, Signal Transduction By P53 Class Mediator
Pathways		MAP2K and MAPK activation	G2/M Checkpoints The role of GTSE1 in G2/M progression after G2 checkpoint
Drugs
Diseases
GWAS
Interacting Genes		36 interacting genes: BAG2 BCAS2 BCL6 CRB3 CRK CRYAA EGLN3 EXOSC1 FAM124B FRS3 GNE GPKOW GTSE1 HNRNPH2 HOXA1 HSPB1 KCTD9 KDM1A KEAP1 LONRF1 LSM3 NOXA1 PARD6A PARD6B PCBP2 PRKAB2 RACK1 SAP30BP SF1 SRSF8 TLX3 TOE1 VAC14 WBP4 ZC3H7A ZNF76	22 interacting genes: AKAP9 CASK CPSF7 CTTN FXR2 GGA1 HNRNPD KAT5 KIFAP3 MAPRE1 MAPRE2 MAPRE3 NIN PHF5A PPIE PRPF39 RBM10 TRNAU1AP UBC WDR83 WEE2-AS1 WTAP
Entrez ID		84292	51512
HPRD ID		14730	09593
Ensembl ID		ENSG00000123154	ENSG00000075218
Uniprot IDs		Q9BRX9	Q9NYZ3
PDB IDs			6QNN 6QNP
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Identical Protein Binding RNA Binding Nucleic Acid Binding Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Processing PAR Polarity Complex RNA Splicing, Via Transesterification Reactions RNA Splicing Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Binding Establishment Or Maintenance Of Apical/basal Cell Polarity MRNA Metabolic Process MRNA Processing Establishment Or Maintenance Of Cell Polarity RNA Metabolic Process MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Precatalytic Spliceosome	MRNA Processing Protein Localization To Microtubule Cytoplasmic Microtubule RNA Splicing Microtubule Plus-end Microtubule Plus-end Binding Spindle Midzone Mitotic Spindle Astral Microtubule End RNA Processing MRNA Metabolic Process Microtubule Organizing Center Regulation Of Microtubule Polymerization Or Depolymerization Pre-mRNA 5'-splice Site Binding Mitotic Spindle Pole Microtubule Cytoskeleton Organization Protein Localization To Cytoskeleton Microtubule-based Process MRNA 5'-splice Site Recognition Positive Regulation Of Cellular Component Organization Regulation Of Microtubule Cytoskeleton Organization RNA Binding Nucleic Acid Binding Regulation Of Microtubule Polymerization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cytoskeleton Organization Positive Regulation Of Protein Polymerization Intracellular Protein Localization RNA Metabolic Process Spindle Assembly Muscle Cell Apoptotic Process U1 SnRNP MRNA Binding Attachment Of Mitotic Spindle Microtubules To Kinetochore Microtubule Cytoskeleton Regulation Of Microtubule-based Process Cellular Component Assembly Positive Regulation Of Organelle Organization Membraneless Organelle Assembly Protein Serine/threonine Kinase Binding Regulation Of Cytoskeleton Organization Nucleic Acid Metabolic Process Regulation Of Organelle Organization Nucleobase-containing Compound Metabolic Process Microtubule Nucleation Regulation Of MRNA Metabolic Process Positive Regulation Of Microtubule Polymerization Centrosome Localization MRNA Splice Site Recognition Microtubule
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