ENKD1 and PDLIM7

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ENKD1	PDLIM7
Gene Name		enkurin domain containing 1	PDZ and LIM domain 7 (enigma)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Microtubule Microtubule Cytoskeleton	Stress Fiber Ruffle Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton
	Molecular Function		Protein Binding Zinc Ion Binding
	Biological Process		Ossification Receptor-mediated Endocytosis Multicellular Organismal Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: APP BEGAIN CALCOCO2 CCDC102B CCDC136 CCDC85B CDR2 CEP70 DGCR6 DVL2 DVL3 FAM102A KRTAP10-5 MDFI MIPOL1 MKRN3 NBPF22P NEFL PDLIM7 PHC2 PLSCR1 PNMA1 PNMA2 PPP1CC RAD54B RBPMS SPERT SPSB3 TRAF2 TRGV7 TRIM54 TSC22D4 UBXN11 YWHAE ZBTB14	34 interactors: AP5B1 BSG C20orf195 CCDC185 DGCR6 ENKD1 GEM GFAP HNRNPD IQGAP1 MDM2 PAK7 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		84080	9260
HPRD ID		13151	10436
Ensembl ID		ENSG00000124074	ENSG00000196923
Uniprot IDs		Q9H0I2	Q9NR12
PDB IDs			2Q3G
Enriched GO Terms of Interacting Partners?		Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAP Kinase Activity Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of Protein Serine/threonine Kinase Activity Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of MAP Kinase Activity Cochlea Morphogenesis Hippo Signaling Non-canonical Wnt Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of Kinase Activity Cochlea Development Positive Regulation Of Protein Kinase Activity Axon Cargo Transport Positive Regulation Of Protein Metabolic Process Positive Regulation Of Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Phosphorylation Response To Stress Regulation Of Protein Tyrosine Kinase Activity Outflow Tract Morphogenesis Regulation Of Phosphorylation Synaptic Growth At Neuromuscular Junction Regulation Of Heart Rate By Hormone Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Protein Modification Process Regulation Of Binding Positive Regulation Of Transferase Activity Neuromuscular Process Controlling Balance Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Neurofilament Bundle Assembly Collateral Sprouting In Absence Of Injury Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Signaling	Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Cell Death Death Response To Organic Substance Immune System Process Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Histone H3-T6 Phosphorylation Apoptotic Process Regulation Of Cellular Protein Metabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Growth Factor Protein Catabolic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Death Blood Coagulation Cellular Protein Modification Process Negative Regulation Of Programmed Cell Death Hemostasis Regulation Of Cellular Process Regulation Of Establishment Of Protein Localization Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Cell Cycle Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
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