ENKD1 and GRHL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ENKD1	GRHL3
Description		enkurin domain containing 1	grainyhead like transcription factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Centriole Spindle Cytoskeleton Microtubule Cytoplasmic Microtubule Plasma Membrane Cilium Microtubule Cytoskeleton Ciliary Basal Body Cell Projection Ciliary Base 9+0 Non-motile Cilium	Chromatin Nucleus Nucleoplasm Cytosol Cilium Actin Cytoskeleton
	Molecular Function	Protein Binding Microtubule Binding Alpha-tubulin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Cell Projection Organization Motile Cilium Assembly Non-motile Cilium Assembly	Establishment Of Planar Polarity Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Pattern Specification Process Ectoderm Development Central Nervous System Development Epidermis Development Gene Expression Positive Regulation Of Gene Expression Regulation Of Actin Cytoskeleton Organization Wound Healing Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Eyelid Development In Camera-type Eye Establishment Of Skin Barrier Cochlea Morphogenesis
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Cleft palate ( 27018472) Fasting blood insulin (BMI interaction) ( 22581228) Male-pattern baldness ( 28196072) Response to interferon beta in multiple sclerosis ( 26644207)
Interacting Genes		208 interacting genes: ABI1 ABI2 ACOT7 ACTMAP AKAP8L ANKRD23 ANKRD49 APP ARMC5 ASB3 AVPI1 BANP BCAS2 BCAS4 BCAT1 BEGAIN BEX3 BLZF1 BRAT1 C18orf54 C1orf105 CALCOCO1 CALCOCO2 CBY1 CBY2 CCDC102B CCDC13 CCDC136 CCDC28B CCDC85B CDCA4 CDPF1 CDR2 CDSN CEP55 CEP70 CHCHD3 CHRDL2 COA7 CTBP2 CYSRT1 DGCR6 DVL2 DVL3 DYDC1 ECM1 EEIG1 EFHC2 EIF4G1 EYA2 EZHIP FAM228A FAM90A1 FCHSD2 FKBP6 FOS FOSB FSD2 GADD45G GADD45GIP1 GET4 GFAP GIGYF1 GOLGA2 GOLGA6A GOLGA6L9 GPRASP3 GRHL3 GRIPAP1 HMBOX1 HNRNPH1 HOMEZ HOOK2 HOXA1 HSF2BP HSPB2 HSPB2-C11orf52 ID2 IGF1 IGFBP6 IKBKG IKZF3 JAKMIP1 KIFC3 KLHL20 KLHL26 KRT14 KRT15 KRT31 KRT35 KRT40 KRTAP10-5 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP4-11 KRTAP5-9 KRTAP6-2 LDOC1 LHX3 LIN7B LMO2 LRRC61 LZTS1 MAPK9 MATN4 MDFI MEIS3 MESD METTL27 MID2 MIF4GD MIPOL1 MISP MKRN3 MLH1 MORN3 MORN5 MRNIP MRPL28 MRPL38 MTUS2 MYF5 MYOZ3 N4BP3 NAB2 NBPF22P NBPF6 NCKIPSD NDUFB7 NEFL NFKBIA NHLRC4 NUTM1 OOEP PAK5 PDLIM7 PDZD4 PHC2 PIBF1 PICK1 PIK3R3 PKNOX2 PLSCR1 PNMA1 PNMA2 POLR3C PPP1CC PPP2R3C PRDM14 PRDM6 RAD54B RBCK1 RBM11 RBPMS RCN1 RUBCN RUNDC3A SLC15A2 SNRNP48 SORBS3 SPAG5 SPDEF SPSB3 SRGAP3 SSC4D STAC3 STXBP4 TENT5B TFIP11 TNNI1 TNS2 TOX2 TRAF1 TRAF2 TRAK1 TRGV7 TRIM23 TRIM27 TRIM35 TRIM54 TSC1 TSC22D4 TSEN15 UBXN11 USH1C USH1G USHBP1 USP20 VBP1 VPS37B VWC2 WDR62 WWOX YWHAE ZBTB14 ZC2HC1C ZFP90 ZNF143 ZNF426 ZNF511 ZNF581 ZNF76 ZRANB1	8 interacting genes: EAF1 ENKD1 GRHL1 GRHL2 PRMT1 PRMT5 PRMT6 RIPPLY1
Entrez ID		84080	57822
HPRD ID		13151	12210
Ensembl ID		ENSG00000124074	ENSG00000158055
Uniprot IDs		Q9H0I2	Q8TE85
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Intermediate Filament Identical Protein Binding Keratin Filament Cytoskeleton Cytosol Intermediate Filament Organization Nucleus Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization	Histone H4R3 Methyltransferase Activity Protein-arginine N-methyltransferase Activity Histone Methyltransferase Activity Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Protein-arginine Omega-N Asymmetric Methyltransferase Activity Methylosome Regulation Of DNA-templated Transcription Methyltransferase Activity Regulation Of RNA Biosynthetic Process Histone H3 Methyltransferase Activity Methyl-CpG Binding Regulation Of RNA Metabolic Process Methylation Protein Methylation Regulation Of Megakaryocyte Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process GATOR1 Complex Binding Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Histone H2AR3 Methyltransferase Activity Epithelium Migration Regulation Of Gene Expression Chromatin DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Peptidyl-arginine N-methylation Histone H3R2 Methyltransferase Activity Macromolecule Methylation Protein-arginine Omega-N Symmetric Methyltransferase Activity Regulation Of Signal Transduction By P53 Class Mediator Epithelial Cell Morphogenesis Involved In Placental Branching Intronic Transcription Regulatory Region Sequence-specific DNA Binding N-methyltransferase Activity Regulation Of Macromolecule Metabolic Process Epidermis Development Anterior Neural Tube Closure Positive Regulation Of Hemoglobin Biosynthetic Process Positive Regulation Of Dopamine Receptor Signaling Pathway Somite Specification Regulation Of Multicellular Organismal Development Nucleoplasm Chromatin Remodeling Cellular Response To Methionine Super Elongation Complex Cell-cell Junction Organization Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine Histone H4 Methyltransferase Activity
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