ENKD1 and CBY1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ENKD1	CBY1
Description		enkurin domain containing 1	chibby 1, beta catenin antagonist
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Centriole Spindle Cytoskeleton Microtubule Cytoplasmic Microtubule Plasma Membrane Cilium Microtubule Cytoskeleton Ciliary Basal Body Cell Projection Ciliary Base 9+0 Non-motile Cilium	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Trans-Golgi Network Centrosome Centriole Cytosol Cytoskeleton Cilium Nuclear Speck Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection
	Molecular Function	Protein Binding Microtubule Binding Alpha-tubulin Binding	Protein Binding Beta-catenin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Establishment Of Mitotic Spindle Orientation Cell Projection Organization Motile Cilium Assembly Non-motile Cilium Assembly	Intracellular Protein Localization Cell Projection Organization Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Floor Plate Development Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription Protein Homotetramerization Cardiac Muscle Cell Differentiation Canonical Wnt Signaling Pathway Cilium Assembly Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		208 interacting genes: ABI1 ABI2 ACOT7 ACTMAP AKAP8L ANKRD23 ANKRD49 APP ARMC5 ASB3 AVPI1 BANP BCAS2 BCAS4 BCAT1 BEGAIN BEX3 BLZF1 BRAT1 C18orf54 C1orf105 CALCOCO1 CALCOCO2 CBY1 CBY2 CCDC102B CCDC13 CCDC136 CCDC28B CCDC85B CDCA4 CDPF1 CDR2 CDSN CEP55 CEP70 CHCHD3 CHRDL2 COA7 CTBP2 CYSRT1 DGCR6 DVL2 DVL3 DYDC1 ECM1 EEIG1 EFHC2 EIF4G1 EYA2 EZHIP FAM228A FAM90A1 FCHSD2 FKBP6 FOS FOSB FSD2 GADD45G GADD45GIP1 GET4 GFAP GIGYF1 GOLGA2 GOLGA6A GOLGA6L9 GPRASP3 GRHL3 GRIPAP1 HMBOX1 HNRNPH1 HOMEZ HOOK2 HOXA1 HSF2BP HSPB2 HSPB2-C11orf52 ID2 IGF1 IGFBP6 IKBKG IKZF3 JAKMIP1 KIFC3 KLHL20 KLHL26 KRT14 KRT15 KRT31 KRT35 KRT40 KRTAP10-5 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP4-11 KRTAP5-9 KRTAP6-2 LDOC1 LHX3 LIN7B LMO2 LRRC61 LZTS1 MAPK9 MATN4 MDFI MEIS3 MESD METTL27 MID2 MIF4GD MIPOL1 MISP MKRN3 MLH1 MORN3 MORN5 MRNIP MRPL28 MRPL38 MTUS2 MYF5 MYOZ3 N4BP3 NAB2 NBPF22P NBPF6 NCKIPSD NDUFB7 NEFL NFKBIA NHLRC4 NUTM1 OOEP PAK5 PDLIM7 PDZD4 PHC2 PIBF1 PICK1 PIK3R3 PKNOX2 PLSCR1 PNMA1 PNMA2 POLR3C PPP1CC PPP2R3C PRDM14 PRDM6 RAD54B RBCK1 RBM11 RBPMS RCN1 RUBCN RUNDC3A SLC15A2 SNRNP48 SORBS3 SPAG5 SPDEF SPSB3 SRGAP3 SSC4D STAC3 STXBP4 TENT5B TFIP11 TNNI1 TNS2 TOX2 TRAF1 TRAF2 TRAK1 TRGV7 TRIM23 TRIM27 TRIM35 TRIM54 TSC1 TSC22D4 TSEN15 UBXN11 USH1C USH1G USHBP1 USP20 VBP1 VPS37B VWC2 WDR62 WWOX YWHAE ZBTB14 ZC2HC1C ZFP90 ZNF143 ZNF426 ZNF511 ZNF581 ZNF76 ZRANB1	18 interacting genes: AGTPBP1 CDK6 CFAP53 CIBAR1 CLU CTNNB1 DDIAS DZIP1L ENKD1 FAM161B GORASP2 LNX1 NBPF11 RALBP1 RASSF10 TNFAIP8L3 TSG101 TTC23L
Entrez ID		84080	25776
HPRD ID		13151	09676
Ensembl ID		ENSG00000124074	ENSG00000100211
Uniprot IDs		Q9H0I2	Q9Y3M2
PDB IDs			4WRQ
Enriched GO Terms of Interacting Partners?		Protein Binding Intermediate Filament Identical Protein Binding Keratin Filament Cytoskeleton Cytosol Intermediate Filament Organization Nucleus Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization	Cytoskeleton Spindle Pole Ciliary Basal Body Cilium Cilium Organization Centriole Cytoplasm Centrosome Organelle Assembly Microtubule Cytoskeleton Cilium Assembly Establishment Of Organelle Localization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Ciliary Transition Zone Cell Projection Cyclin D3-CDK6 Complex T Cell Differentiation In Thymus Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex Negative Regulation Of Myeloid Leukocyte Differentiation FBXO Family Protein Binding Establishment Of Protein Localization To Vacuole Perinuclear Endoplasmic Reticulum Lumen Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Neuronal Signal Transduction Cellular Component Assembly Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Positive Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Glial Cell Fate Determination Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Organelle Localization Renal Outer Medulla Development Renal Vesicle Formation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Extracellular Transport Positive Regulation Of Ubiquitin-dependent Endocytosis Doxorubicin Transport
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