ENKD1 and BEGAIN

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ENKD1	BEGAIN
Gene Name		enkurin domain containing 1	brain-enriched guanylate kinase-associated
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Microtubule Microtubule Cytoskeleton	Cytoplasm Membrane Dendrite Neuronal Cell Body
	Molecular Function		Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS			Menarche (age at onset) ( 21102462)
Protein-Protein Interactions		35 interactors: APP BEGAIN CALCOCO2 CCDC102B CCDC136 CCDC85B CDR2 CEP70 DGCR6 DVL2 DVL3 FAM102A KRTAP10-5 MDFI MIPOL1 MKRN3 NBPF22P NEFL PDLIM7 PHC2 PLSCR1 PNMA1 PNMA2 PPP1CC RAD54B RBPMS SPERT SPSB3 TRAF2 TRGV7 TRIM54 TSC22D4 UBXN11 YWHAE ZBTB14	23 interactors: ABLIM1 APP BAHD1 CATSPER1 DEF6 DLG1 DLG4 DTNB ENKD1 FAM107A GFI1B HGS HID1 KIAA0408 QSOX1 RBL1 RIBC2 TRIM27 USP2 ZFP64 ZNF250 ZNF417 ZNF774
Entrez ID		84080	57596
HPRD ID		13151	06459
Ensembl ID		ENSG00000124074	ENSG00000183092
Uniprot IDs		Q9H0I2	Q9BUH8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAP Kinase Activity Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of Protein Serine/threonine Kinase Activity Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of MAP Kinase Activity Cochlea Morphogenesis Hippo Signaling Non-canonical Wnt Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of Kinase Activity Cochlea Development Positive Regulation Of Protein Kinase Activity Axon Cargo Transport Positive Regulation Of Protein Metabolic Process Positive Regulation Of Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Phosphorylation Response To Stress Regulation Of Protein Tyrosine Kinase Activity Outflow Tract Morphogenesis Regulation Of Phosphorylation Synaptic Growth At Neuromuscular Junction Regulation Of Heart Rate By Hormone Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Protein Modification Process Regulation Of Binding Positive Regulation Of Transferase Activity Neuromuscular Process Controlling Balance Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Neurofilament Bundle Assembly Collateral Sprouting In Absence Of Injury Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Signaling	Receptor Localization To Synapse Regulation Of Metabolic Process Protein Localization To Synapse Regulation Of Gene Expression Cell Recognition Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Cortical Actin Cytoskeleton Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Establishment Or Maintenance Of Apical/basal Cell Polarity Axon Guidance Cortical Cytoskeleton Organization Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Ion Transmembrane Transport Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Receptor Clustering Axonogenesis Response To Brefeldin A Locomotory Behavior Gene Expression Negative Regulation Of Cellular Metabolic Process Nucleotide Phosphorylation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cell-cell Recognition Chemotaxis Regulation Of Membrane Potential Regulation Of Ion Transport Negative Regulation Of Transcription, DNA-templated Neuron Projection Morphogenesis Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Gene Expression, Epigenetic Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Neuromuscular Process Controlling Balance Synapse Assembly Negative Regulation Of RNA Biosynthetic Process Regulation Of ERBB Signaling Pathway Collateral Sprouting In Absence Of Injury Cell Morphogenesis Involved In Differentiation
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