ULK1 and GABARAPL2

Number of citations of the paper that reports this interaction (PMID 11146101)
34

Data Source:
HPRD (two hybrid, in vitro)

		ULK1	GABARAPL2
Gene Name		unc-51 like autophagy activating kinase 1	GABA(A) receptor-associated protein-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Autophagic Vacuole Cytosol Cytoplasmic Vesicle Membrane Pre-autophagosomal Structure Membrane ATG1/UKL1 Signaling Complex Neuron Projection Neuronal Cell Body ULK1-ATG13-FIP200 Complex Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Pre-autophagosomal Structure Membrane Extrinsic Component Of Autophagic Vacuole Membrane	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Cytoplasm Autophagic Vacuole Golgi Apparatus Cytosol Extrinsic Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Rab GTPase Binding Protein Kinase Binding Protein Complex Binding	SNARE Binding Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding
	Biological Process	Autophagic Vacuole Assembly Protein Phosphorylation Ras Protein Signal Transduction Protein Localization Regulation Of Autophagy Positive Regulation Of Autophagy Positive Regulation Of Macroautophagy Cerebellar Granule Cell Differentiation Radial Glia Guided Migration Of Cerebellar Granule Cell Neuron Projection Regeneration Neuron Projection Development Receptor Internalization Cellular Response To Nutrient Levels Response To Starvation Protein Autophosphorylation Negative Regulation Of Collateral Sprouting Axon Extension Regulation Of Neurotrophin TRK Receptor Signaling Pathway	Autophagic Vacuole Assembly Mitochondrion Degradation Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Positive Regulation Of ATPase Activity Nucleophagy Membrane Fusion Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: EXOC8 GABARAP GABARAPL2 MBP PPP1CA SDCBP SESN2 SQSTM1 SYNGAP1	50 interactors: AAMP AGTRAP AHNAK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CCDC155 CLN8 EGFR FUNDC1 GIMAP6 GOSR1 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MLX NBR1 NSF PTPRA RAP1A RAP2A RCN2 RPS2 SGTA SIK2 SQSTM1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP2 TSR2 UBA5 ULK1 ULK2 VDR YWHAZ
Entrez ID		8408	11345
HPRD ID		11933	16246
Ensembl ID		ENSG00000177169	ENSG00000034713
Uniprot IDs		O75385	P60520
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Organization Autophagy Macroautophagy Response To External Stimulus Cellular Response To Starvation Protein Localization Nucleophagy Cellular Response To Nutrient Levels Response To Starvation Mitochondrion Degradation Cellular Response To Extracellular Stimulus Cellular Localization Cell Communication Organelle Disassembly Autophagic Vacuole Assembly Negative Regulation Of Axonogenesis Catabolic Process Cellular Component Assembly Mitochondrion Organization Exocyst Assembly Establishment Of Localization In Cell Response To Nutrient Levels Response To Extracellular Stimulus Negative Regulation Of Cell Morphogenesis Involved In Differentiation Vacuole Organization Regulation Of Glucose Metabolic Process Negative Regulation Of Neuron Projection Development Regulation Of Phosphorylation Signaling Cellular Protein Localization Membrane Fusion Defense Response To Nematode Synaptic Transmission Protein Transport Negative Regulation Of Cell Projection Organization Response To Stimulus Cellular Lipid Catabolic Process Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Regulation Of Axonogenesis Intracellular Transport Exocyst Localization Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Neuron Differentiation Response To Nematode Cellular Response To Stimulus Ras Protein Signal Transduction	Autophagy Macroautophagy Response To Starvation Cellular Response To Nutrient Levels Cellular Response To Starvation Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Vacuole Organization Mitochondrion Degradation Organelle Disassembly Nucleophagy Membrane Organization Positive Regulation Of Autophagy Response To Stress Cellular Response To Nitrogen Starvation Catabolic Process Regulation Of Autophagy Response To External Stimulus Protein Localization Establishment Of Protein Localization Protein Delipidation Mitochondrion Organization Cellular Response To Stress Positive Regulation Of Metabolic Process Organelle Assembly C-terminal Protein Lipidation Establishment Of Protein Localization To Membrane Protein Localization To Membrane Protein Transport Positive Regulation Of Cellular Metabolic Process Intracellular Transport Cellular Localization Cell Communication Positive Regulation Of Macroautophagy Cellular Component Assembly Response To Stimulus Establishment Of Localization In Cell Cellular Response To Stimulus Protein Targeting To Membrane Regulation Of Signaling Regulation Of Signal Transduction Organelle Organization Cellular Metabolic Process Protein Lipidation Lipoprotein Biosynthetic Process Negative Regulation Of Collateral Sprouting Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity
Tagcloud ?		antiretroviral antiviral ascribed assemble atg8 autophagic autophagy becn1 cargo constitutes defines destruction establishes exemplified explains hitherto machinery nucleate platforms preparation recognizes regulators reminiscent restriction trim trim5 trim5alpha trims tripartite
Tagcloud (Difference) ?		antiretroviral antiviral ascribed assemble atg8 autophagic autophagy becn1 cargo constitutes defines destruction establishes exemplified explains hitherto machinery nucleate platforms preparation recognizes regulators reminiscent restriction trim trim5 trim5alpha trims tripartite
Tagcloud (Intersection) ?