SLC9A3R2 and SLCO1A2

Number of citations of the paper that reports this interaction (PMID 15553237)
5

Data Source:
HPRD (two hybrid)

		SLC9A3R2	SLCO1A2
Gene Name		solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	solute carrier organic anion transporter family, member 1A2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding	Organic Anion Transmembrane Transporter Activity
	Biological Process	Protein Complex Assembly Negative Regulation Of Phosphatidylinositol 3-kinase Signaling	Bile Acid Metabolic Process Organic Anion Transport Bile Acid And Bile Salt Transport Sodium-independent Organic Anion Transport Small Molecule Metabolic Process Transmembrane Transport
Pathways			Bile acid and bile salt metabolism Metabolism of lipids and lipoproteins Recycling of bile acids and salts Transport of vitamins, nucleosides, and related molecules SLC-mediated transmembrane transport Transport of organic anions
Drugs
Diseases
GWAS			Bilirubin levels ( 19414484) Methotrexate phramacokinetics (acute lymphoblastic leukemia) ( 19901119) Progressive supranuclear palsy ( 21685912)
Protein-Protein Interactions		35 interactors: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDPK1 PDZK1 PIK3CA PLCB3 PODXL PRKACA PTEN PTH1R RDX SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1	4 interactors: PDZD3 PDZK1 SLC9A3R1 SLC9A3R2
Entrez ID		9351	6579
HPRD ID		05946	09112
Ensembl ID		ENSG00000065054	ENSG00000084453
Uniprot IDs		Q15599	P46721
PDB IDs		2D11 2HE4 2OCS
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Kinase Activity Ion Homeostasis Transmembrane Transport Regulation Of Kinase Activity Regulation Of Ion Transport Positive Regulation Of Ion Transport Regulation Of Protein Phosphorylation Homeostatic Process Positive Regulation Of Transport Ion Transport Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Phosphorylation Ion Transmembrane Transport Cellular Cation Homeostasis Organic Anion Transport Cellular Ion Homeostasis Cytosolic Calcium Ion Homeostasis Chemical Homeostasis Positive Regulation Of Protein Kinase Activity Blood Circulation Positive Regulation Of Cellular Protein Metabolic Process Anion Transport Platelet Activation Positive Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Transport Positive Regulation Of Protein Phosphorylation Sodium-independent Organic Anion Transport Carnitine Transport Cellular Chemical Homeostasis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Body Fluid Levels Monocarboxylic Acid Transport Sperm Capacitation Anion Transmembrane Transport Regulation Of Cellular Component Organization Sodium Ion Transport Inorganic Anion Transport Regulation Of Cellular Protein Metabolic Process Response To Organonitrogen Compound Regulation Of Ion Transmembrane Transport Blood Coagulation Hemostasis Activation Of Protein Kinase Activity Positive Regulation Of Phosphorylation Quaternary Ammonium Group Transport Positive Regulation Of Cytosolic Calcium Ion Concentration See more	Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of CGMP Biosynthetic Process Renal Phosphate Ion Absorption Negative Regulation Of Guanylate Cyclase Activity Monocarboxylic Acid Transport Glutathione Transport Negative Regulation Of Sodium:proton Antiporter Activity Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium:proton Antiporter Activity Carboxylic Acid Transport Organic Acid Transport Negative Regulation Of Sodium Ion Transmembrane Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Ion Transport Bile Acid Secretion CGMP-mediated Signaling Receptor Guanylyl Cyclase Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Regulation Of Ion Transmembrane Transport Oligopeptide Transport Carnitine Transport Organic Anion Transport Negative Regulation Of Sodium Ion Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Renal Absorption Regulation Of Proton Transport Phosphate Ion Homeostasis Microvillus Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Quaternary Ammonium Group Transport Regulation Of CGMP Biosynthetic Process Negative Regulation Of Lyase Activity Regulation Of Ion Transport Regulation Of Excretion Monovalent Inorganic Cation Transport Anion Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Cyclic-nucleotide-mediated Signaling Bile Acid And Bile Salt Transport Regulation Of CGMP Metabolic Process Positive Regulation Of Protein Targeting To Membrane Dopamine Receptor Signaling Pathway Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Nucleotide Metabolic Process See more
Tagcloud ?			abcc abcc1 abcc3 abcc4 abcc5 abcc6 accessibility astrocytic chemoresistance formerly gliomas mrp1 mrp6 oatp oatp1a2 oatp1b1 oatp1b3 oatp1c1 oatp2b1 oatp4a1 oligoastrocytomas oligodendrogliomas pcrs portions pumps transporters
Tagcloud (Difference) ?			abcc abcc1 abcc3 abcc4 abcc5 abcc6 accessibility astrocytic chemoresistance formerly gliomas mrp1 mrp6 oatp oatp1a2 oatp1b1 oatp1b3 oatp1c1 oatp2b1 oatp4a1 oligoastrocytomas oligodendrogliomas pcrs portions pumps transporters
Tagcloud (Intersection) ?