SOX7 and GLRX3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SOX7	GLRX3
Gene Name		SRY (sex determining region Y)-box 7	glutaredoxin 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cell Cortex Z Disc Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	Protein Kinase C Binding Protein Binding Electron Carrier Activity Protein Disulfide Oxidoreductase Activity Poly(A) RNA Binding Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Endoderm Formation Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Cell Proliferation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Canonical Wnt Signaling Pathway	Regulation Of The Force Of Heart Contraction Negative Regulation Of Cardiac Muscle Hypertrophy Cell Redox Homeostasis Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS		Retinal vascular caliber ( 21060863)	HIV-1 susceptibility ( 21160409)
Protein-Protein Interactions		4 interactors: APP GLRX3 SMAD5 SMAD7	57 interactors: ADAMTSL4 ALKBH3 BOLA1 CBLB CGGBP1 CIAPIN1 EFEMP2 FAM118A FRA10AC1 GMCL1 GRN HEXDC IKZF1 KRT31 KRT38 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE2D MAP3K3 MAPK6 MAPKBP1 MOXD1 NADK NOTCH2NL OLFM3 PCSK5 PFDN5 PLSCR1 PRKCQ PRKCZ PRKD2 RGS20 SOX7 STAU1 TCF4 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF148 ZNF426 ZNF512B ZNF544
Entrez ID		83595	10539
HPRD ID		18087	10153
Ensembl ID		ENSG00000171056	ENSG00000108010
Uniprot IDs		Q9BT81	O76003
PDB IDs			2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?		BMP Signaling Pathway Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Kidney Epithelium Development Regulation Of Heart Contraction Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Collateral Sprouting In Absence Of Injury Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Phosphorylation Positive Regulation Of Transcription, DNA-templated Homeostatic Process Collateral Sprouting Axon Midline Choice Point Recognition Mullerian Duct Regression Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Kidney Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Axon Choice Point Recognition Regulation Of Cell Differentiation Renal System Development Negative Regulation Of Cell Development Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription By Competitive Promoter Binding Neuron Remodeling Osteoblast Fate Commitment Urogenital System Development Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Muscle Hypertrophy Phosphorylation Pathway-restricted SMAD Protein Phosphorylation Posttranscriptional Regulation Of Gene Expression Cellular Protein Complex Localization Regulation Of Cellular Ketone Metabolic Process Anatomical Structure Regression Response To Laminar Fluid Shear Stress Negative Regulation Of Peptidyl-threonine Phosphorylation Cellular Copper Ion Homeostasis Protein Complex Localization	Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Positive Regulation Of Interleukin-4 Production Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Interleukin-4 Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of Cell Activation Regulation Of T Cell Activation Cell Death Death Multicellular Organismal Development Positive Regulation Of Interleukin-2 Production Positive Regulation Of Alpha-beta T Cell Differentiation Positive Regulation Of Epithelial Cell Proliferation Anatomical Structure Development Positive Regulation Of Neutrophil Differentiation Renin Secretion Into Blood Stream Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cellular Process Transcription, DNA-templated Regulation Of T Cell Receptor Signaling Pathway Embryonic Digestive Tract Development Positive Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Positive Regulation Of Protein Metabolic Process Regulation Of Signal Transduction RNA Biosynthetic Process Regulation Of Lymphocyte Activation Protein Kinase D Signaling Positive Regulation Of T-helper 2 Cell Activation Oxidative Single-stranded DNA Demethylation Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure Platelet Activation Regulation Of Insulin Receptor Signaling Pathway Apoptotic Process Positive Regulation Of T Cell Activation
Tagcloud ?		anchorage bioinformatics box carcinogenesis determining downregulation ectopic emerged kinds luciferase messenger microrna micrornas mir mirnas onco participates promoted regulators repressed silenced sum suppressing translational tumorigenesis untranslated utr y zr
Tagcloud (Difference) ?		anchorage bioinformatics box carcinogenesis determining downregulation ectopic emerged kinds luciferase messenger microrna micrornas mir mirnas onco participates promoted regulators repressed silenced sum suppressing translational tumorigenesis untranslated utr y zr
Tagcloud (Intersection) ?