SOX7

Description		SRY-box transcription factor 7
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Endoderm Formation Regulation Of Transcription By RNA Polymerase II Tissue Development Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis
Pathways		Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		A body shape index ( 34021172) Alanine aminotransferase levels ( 33547301) Anxiety/tension (special factor of neuroticism) ( 30867560) Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Autism spectrum disorder ( 30804558) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Gut microbiota (beta diversity) ( 27723756) HDL cholesterol levels ( 32203549) Intracranial aneurysm ( 29531279) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lymphocyte count ( 27863252 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Neutrophil percentage of white cells ( 32888494) Number of sexual partners ( 30643258) Processed meat consumption ( 32066663) Refractive error ( 32231278) Retinal vascular caliber ( 21060863) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride levels ( 32154731) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494 27863252)
Novel Interacting Genes		3 novel interacting genes: DLC1 LZTS1 MTUS1
Interacting Genes		5 interacting genes: APP GLRX3 SCAI SMAD5 SMAD7
Entrez ID		83595
HPRD ID		18087
Ensembl ID		ENSG00000171056
Uniprot IDs		Q9BT81
PDB IDs
Enriched GO Terms of Interacting Partners?		Heteromeric SMAD Protein Complex Regulation Of Cell Migration Regulation Of Locomotion Regulation Of Cell Motility I-SMAD Binding Negative Regulation Of Rho Protein Signal Transduction SMAD Protein Signal Transduction Regulation Of Cell Junction Assembly Regulation Of Blood Circulation Negative Regulation Of Signaling Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Ureteric Bud Development Mesonephric Epithelium Development Mesonephric Tubule Development Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Response To Growth Factor Amylin Binding Positive Regulation Of Toll Signaling Pathway Intracellular Iron Ion Homeostasis Kidney Epithelium Development Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Cell Migration Negative Regulation Of Small GTPase Mediated Signal Transduction Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Regulation Of Rho Protein Signal Transduction Cytoplasm Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Negative Regulation Of Fas Signaling Pathway Positive Regulation Of Chondrocyte Development Hindbrain Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Cell Junction Organization PTB Domain Binding Monoatomic Ion Homeostasis Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium
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