F8A1 and SNTA1

Number of citations of the paper that reports this interaction (PubMedID 15123239)
0

Data Source:
BioGRID (unspecified method)

		F8A1	SNTA1
Description		coagulation factor VIII associated 1	syntrophin alpha 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Nuclear Body	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Anchoring Junction
	Molecular Function	Protein Binding	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Transmembrane Transporter Binding Nitric-oxide Synthase Binding ATPase Binding
	Biological Process	Vesicle Cytoskeletal Trafficking Negative Regulation Of Proteasomal Protein Catabolic Process	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport
Pathways			Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases			Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS			HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)
Interacting Genes		6 interacting genes: DNMT3A HTT MTNR1A SH3GLB1 SNTA1 TLR10	76 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB ENTREP3 F8A1 FABP1 GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TIAM1 TLX3 TRA TRBV12-3 UTRN VANGL2 XRCC6
Entrez ID		8263	6640
HPRD ID		02374	03009
Ensembl ID		ENSG00000288722	ENSG00000101400
Uniprot IDs		P23610	B3KTR0 Q13424
PDB IDs		6EZ8 6X9O 7DXJ 7DXK 8SAH 8VLX 8W15
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Response To Hypoxia Protein-cysteine Methyltransferase Activity Cellular Response To Bisphenol A Identical Protein Binding DNA (cytosine-5-)-methyltransferase Activity Regulation Of CAMKK-AMPK Signaling Cascade Transmembrane Transporter Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Macroautophagy Positive Regulation Of Organelle Assembly Positive Regulation Of Autophagy Positive Regulation Of Aggrephagy Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Lipophagy Protein-containing Complex Positive Regulation Of CAMKK-AMPK Signaling Cascade Melatonin Receptor Activity Syntrophin Complex 'de Novo' Post-translational Protein Folding Positive Regulation Of Membrane Tubulation Autophagic Cell Death Protein Localization To Vacuolar Membrane Toll-like Receptor 2 Binding Regulation Of Macroautophagy Receptor Complex Autosome Genomic Imprinting Response To Bisphenol A Cell Death Apoptotic Process Programmed Cell Death Vocal Learning Phosphatidylinositol 3-kinase Activator Activity Lipopeptide Binding Unmethylated CpG Binding Profilin Binding Observational Learning Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Organelle Assembly Lysophosphatidic Acid Acyltransferase Activity 'de Novo' Protein Folding Cellular Response To Bacterial Lipopeptide Regulation Of Monoatomic Ion Transmembrane Transport Nitric-oxide Synthase Binding Response To Bacterial Lipoprotein Transposable Element Silencing By PiRNA-mediated DNA Methylation Response To Vitamin A XY Body Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Cellular Response To Ethanol Auditory Behavior	Plasma Membrane System Process Regulation Of System Process Membrane G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity Regulation Of Blood Circulation Circulatory System Process Vascular Process In Circulatory System Monoatomic Ion Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Heart Contraction Blood Vessel Diameter Maintenance Regulation Of Tube Size Basolateral Plasma Membrane Monoatomic Ion Transmembrane Transport Regulation Of Biological Quality Transmembrane Transport Muscle Contraction Inorganic Ion Transmembrane Transport Metal Ion Transport Monoatomic Ion Transport Regulation Of Heart Rate Inorganic Cation Transmembrane Transport Regulation Of Membrane Potential Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Cardiac Muscle Cell Action Potential Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Muscle System Process Synapse Inward Rectifier Potassium Channel Activity Synaptic Signaling Vasodilation Intracellular Signaling Cassette Regulation Of Monoatomic Ion Transmembrane Transport Adrenergic Receptor Activity CGMP-mediated Signaling Calcium-mediated Signaling Action Potential Potassium Ion Transport Regulation Of Blood Pressure Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Voltage-gated Sodium Channel Complex Signal Transduction Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Multicellular Organismal Process
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