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VANGL1 and DVL1
Number of citations of the paper that reports this interaction (PubMedID
15456783
)
0
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
VANGL1
DVL1
Description
VANGL planar cell polarity protein 1
dishevelled segment polarity protein 1
Image
GO Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Membrane
Lateral Plasma Membrane
Cytoplasm
Cytosol
Microtubule
Plasma Membrane
Postsynaptic Density
Microtubule Cytoskeleton
Membrane
Lateral Plasma Membrane
Clathrin-coated Vesicle
Axon
Dendrite
Growth Cone
Cytoplasmic Vesicle
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Synapse
Schaffer Collateral - CA1 Synapse
Presynapse
Glutamatergic Synapse
Neuronal Dense Core Vesicle
Wnt Signalosome
Molecular Function
Protein Binding
Frizzled Binding
Protein Binding
Beta-catenin Binding
Enzyme Binding
Protein Kinase Binding
Small GTPase Binding
Identical Protein Binding
Biological Process
Pigmentation
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Mucociliary Clearance
Heart Looping
Outflow Tract Morphogenesis
Regulation Of DNA-templated Transcription
Neurotransmitter Secretion
Axonogenesis
Axon Guidance
Neuromuscular Junction Development
Positive Regulation Of Neuron Projection Development
Wnt Signaling Pathway
Synaptic Vesicle Exocytosis
Neural Tube Development
Convergent Extension Involved In Neural Plate Elongation
Cytoplasmic Microtubule Organization
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Localization
Protein Localization To Nucleus
Social Behavior
Protein Localization To Microtubule
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Receptor Clustering
Positive Regulation Of Transcription By RNA Polymerase II
Collateral Sprouting
Axon Extension
Dendrite Morphogenesis
Synapse Organization
Protein Stabilization
Convergent Extension Involved In Organogenesis
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Prepulse Inhibition
Dendritic Spine Morphogenesis
Skeletal Muscle Acetylcholine-gated Channel Clustering
Cochlea Morphogenesis
Presynapse Assembly
Postsynapse Organization
Regulation Of Postsynapse Organization
Positive Regulation Of Neuron Projection Arborization
Positive Regulation Of Protein Localization To Presynapse
Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
RHOA GTPase cycle
RHOB GTPase cycle
RHOC GTPase cycle
CDC42 GTPase cycle
RAC1 GTPase cycle
RAC2 GTPase cycle
RHOD GTPase cycle
RHOQ GTPase cycle
RHOH GTPase cycle
RHOG GTPase cycle
RHOJ GTPase cycle
RHOU GTPase cycle
RAC3 GTPase cycle
RHOV GTPase cycle
RHOF GTPase cycle
RND3 GTPase cycle
RND2 GTPase cycle
RND1 GTPase cycle
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
PCP/CE pathway
PCP/CE pathway
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
Spina bifida
Caudal regression syndrome and Sirenomelia
GWAS
Coronary artery disease (
33020668
)
Gut microbiota (bacterial taxa) (
27694959
)
Iron status biomarkers (ferritin levels) (
33536631
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Optic disc size (
31809533
)
Inflammatory bowel disease (
28067908
)
Nicotine dependence (
32281736
)
Ulcerative colitis (
28067908
)
Interacting Genes
12 interacting genes:
CD82
DVL1
DVL2
DVL3
GMFG
LINC00839
NT5C3A
RAPGEF5
SMYD3
SRPK1
THAP2
UBC
45 interacting genes:
ANXA7
ARRB1
ATN1
AXIN1
BAG3
BRD7
BUB1
CCDC88C
CSNK1D
CSNK1E
CSNK2A1
CTNNB1
CXXC4
DAAM1
DAB2
DVL3
DYNLT1
EPS8
FBXW7
FRAT1
FZD7
GNAI3
HDHD2
HECW1
LRRK2
MLH3
MSH2
NCK2
NEDD4
PPM1A
PSMA3
RAC1
RB1
SIPA1
SMAD1
SMAD2
SMAD3
SMAD4
SMAD7
SMYD1
SNCA
TRIM69
USP13
VANGL1
VANGL2
Entrez ID
81839
1855
HPRD ID
18279
03220
Ensembl ID
ENSG00000173218
ENSG00000107404
Uniprot IDs
Q8TAA9
O14640
PDB IDs
8ZXD
9JK6
9JK8
9JK9
6LCA
6LCB
6TTK
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Neuron Projection Arborization
Regulation Of Neuron Projection Arborization
Convergent Extension Involved In Neural Plate Elongation
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Frizzled Binding
Convergent Extension Involved In Organogenesis
Non-canonical Wnt Signaling Pathway
Convergent Extension Involved In Gastrulation
Regulation Of Cell Morphogenesis
Convergent Extension
Canonical Wnt Signaling Pathway
Positive Regulation Of Cell Projection Organization
Cochlea Morphogenesis
Regulation Of Cytoskeleton Organization
Positive Regulation Of Protein Localization To Presynapse
Wnt Signaling Pathway
Small GTPase Binding
Clathrin-coated Vesicle
Outflow Tract Morphogenesis
Lateral Plasma Membrane
Heart Looping
Embryonic Heart Tube Morphogenesis
Regulation Of Cell Projection Organization
Actin Filament Debranching
TRNA 2'-phosphotransferase Activity
Regulation Of Actin Cytoskeleton Organization
Protein Phosphorylation
Beta-catenin Binding
Nuclear Body
Regulation Of Actin Filament-based Process
Positive Regulation Of JNK Cascade
Phosphorylation
Epithelial Tube Morphogenesis
Regulation Of Anatomical Structure Morphogenesis
Cytoplasmic Vesicle
Histone H3K36 Dimethyltransferase Activity
Wnt Signaling Pathway
Regulation Of Wnt Signaling Pathway
I-SMAD Binding
Regulation Of Canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway
Cell Surface Receptor Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Regulation Of Signal Transduction
Heteromeric SMAD Protein Complex
Regulation Of Protein Catabolic Process
Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Positive Regulation Of Protein Catabolic Process
Ubiquitin Protein Ligase Binding
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Positive Regulation Of Signal Transduction
Positive Regulation Of Metabolic Process
Positive Regulation Of Catabolic Process
SMAD Protein Complex
Cytoplasm
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Wnt Signaling Pathway
Positive Regulation Of Macromolecule Metabolic Process
SMAD Protein Signal Transduction
Negative Regulation Of Signal Transduction
Canonical Wnt Signaling Pathway
Response To Growth Factor
R-SMAD Binding
Positive Regulation Of Protein Metabolic Process
Embryonic Pattern Specification
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Developmental Process
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Intracellular Signal Transduction
Regulation Of Protein Stability
Cellular Response To Growth Factor Stimulus
Dorsal/ventral Axis Specification
Regulation Of Cellular Component Organization
Cytosol
Negative Regulation Of Biosynthetic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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