SF3A2 and WBP4

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		SF3A2	WBP4
Gene Name		splicing factor 3a, subunit 2, 66kDa	WW domain binding protein 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression	MRNA Cis Splicing, Via Spliceosome
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Crohn's disease ( 23266558)
Protein-Protein Interactions		8 interactors: APBB1 HTATSF1 PRPF40A RETN SF3A1 SMURF2 TCERG1 WBP4	44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207
Entrez ID		8175	11193
HPRD ID		02877	16086
Ensembl ID		ENSG00000104897	ENSG00000120688
Uniprot IDs		Q05DF2 Q15428	B7Z4M2 O75554
PDB IDs			2DK1 2JXW
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Splicing Nitrogen Compound Metabolic Process MRNA Processing Negative Regulation Of Thymidylate Synthase Biosynthetic Process MRNA Metabolic Process RNA Processing Positive Regulation Of Progesterone Secretion Regulation Of Progesterone Secretion MRNA 3'-splice Site Recognition Regulation Of Transcription From RNA Polymerase II Promoter Ubiquitin-dependent SMAD Protein Catabolic Process Negative Regulation Of Feeding Behavior MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Female Gonad Development Transcription, DNA-templated Regulation Of Feeding Behavior RNA Biosynthetic Process MRNA Cis Splicing, Via Spliceosome	MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress
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