TRIM8 and USP7

  • Number of citations of the paper that reports this interaction (PMID 21988832)
  • 14
  • Data Source:
  • BioGRID (two hybrid)

TRIM8

USP7

Gene Name tripartite motif containing 8 ubiquitin specific peptidase 7 (herpes virus-associated)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 45 interactors: BRAP CBL CCNH ITSN1 MAP3K7 MKRN3 MSL2 OTUB2 PCGF5 RAD18 RC3H2 RCHY1 RNF111 RNF113A RNF138 RNF141 RNF181 RNF41 RNF7 SIAH1 SOCS1 TNFAIP3 TRAF5 TRIM15 TRIM2 TRIM21 TRIM24 TRIM25 TRIM39 TRIM43 TRIM47 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L6 UBE2V1 UBE2W UHRF2 USP2 USP21 USP39 USP7 XIAP 85 interactors: ACD ARNT2 ATXN1 BCOR BEND5 BMI1 CBX8 CHEK1 CLSPN CREB3L3 DAXX DNAJA3 DNMT1 DNMT3A EWSR1 EZH2 FAM175B FOXN2 HECW1 HERPUD1 HIST3H2BB HTRA2 KAT5 KLHL8 MAGEE1 MAL MARCH7 MCMBP MDM2 MDM4 MYD88 NECAB2 PCGF2 PEG3 PEPD PHLDB2 PICK1 PJA1 PLA2G2A PLEKHO1 PPARG PPL RADIL RARA RB1 RBCK1 RELA RFFL RING1 RNF2 RNF220 SMAD3 SUMO1 SUZ12 SYVN1 TANK TBCB TMPO TP53 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TRIM22 TRIM27 TRIM31 TRIM54 TRIM55 TRIM63 TRIM8 TRO UBC UBE2E1 UBE2S UHRF2 USP15 USP21 USP28 WWP2 XPC ZEB1 ZMYND8 ZNF423
Entrez ID 81603 7874
HPRD ID 06934 03950
Ensembl ID ENSG00000171206 ENSG00000187555
Uniprot IDs Q9BZR9 B7Z815 Q6U8A4 Q93009
PDB IDs 1NB8 1NBF 1YY6 1YZE 2F1W 2F1X 2F1Y 2F1Z 2FOJ 2FOO 2FOP 2KVR 2XXN 2YLM 3MQR 3MQS 4JJQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aggressive  ccrcc  chemotherapeutic  cytotoxic  defective  deficit  define  dramatically  enhancer  impairing  impairs  inactivated  inactivation  link  mdm2  mechanistic  modulator  p53  rcc  re  regulators  renders  restoring  stabilizes  suppress  treating  tumours  way  wild 
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mdm2  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
Tagcloud (Difference) ?
aggressive  ccrcc  chemotherapeutic  cytotoxic  defective  deficit  define  dramatically  enhancer  impairing  impairs  inactivated  inactivation  link  mechanistic  modulator  p53  rcc  re  regulators  renders  restoring  stabilizes  suppress  treating  tumours  way  wild 
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
Tagcloud (Intersection) ?
mdm2