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COL18A1 and ITGA5
Number of citations of the paper that reports this interaction (PMID
11158588
)
65
Data Source:
HPRD
(in vivo)
COL18A1
ITGA5
Gene Name
collagen, type XVIII, alpha 1
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Extracellular Vesicular Exosome
Ruffle
Cytoplasm
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Ruffle Membrane
Synapse
Alphav-beta3 Integrin-vitronectin Complex
Molecular Function
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Metal Ion Binding
Epidermal Growth Factor Receptor Binding
Platelet-derived Growth Factor Receptor Binding
Integrin Binding
Protein Binding
Vascular Endothelial Growth Factor Receptor 2 Binding
Metal Ion Binding
Biological Process
Angiogenesis
Endothelial Cell Morphogenesis
Cell Adhesion
Visual Perception
Positive Regulation Of Cell Proliferation
Negative Regulation Of Cell Proliferation
Organ Morphogenesis
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Positive Regulation Of Cell Migration
Collagen Catabolic Process
Response To Drug
Response To Hydrostatic Pressure
Positive Regulation Of Endothelial Cell Apoptotic Process
Angiogenesis
Cell-substrate Junction Assembly
Cell Adhesion
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Leukocyte Cell-cell Adhesion
Integrin-mediated Signaling Pathway
Axon Guidance
Blood Coagulation
Memory
Positive Regulation Of Cell-substrate Adhesion
Viral Process
Extracellular Matrix Organization
Positive Regulation Of Cell Migration
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell-substrate Adhesion
Cell-cell Adhesion Mediated By Integrin
Heterotypic Cell-cell Adhesion
Wound Healing, Spreading Of Epidermal Cells
Endodermal Cell Differentiation
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Leukocyte Migration
Negative Regulation Of Anoikis
Pathways
Collagen formation
Laminin interactions
Collagen degradation
Activation of Matrix Metalloproteinases
Integrin cell surface interactions
Collagen biosynthesis and modifying enzymes
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Signal transduction by L1
Axon guidance
Elastic fibre formation
Fibronectin matrix formation
L1CAM interactions
Integrin cell surface interactions
Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Hippocampal atrophy (
22745009
)
Protein-Protein Interactions
8 interactors:
CTSL
FBLN2
GPC1
GPC4
HNRNPD
ITGA5
KDR
MMP2
24 interactors:
ANGPT1
ANGPTL3
ARHGAP5
AUP1
CD9
COL18A1
COL1A1
EGFR
ERBB2
FGFR2
FLT4
FN1
GIPC1
GRK6
ITGB1
ITGB3
ITGB5
L1CAM
NISCH
PECAM1
RABIF
SPP1
STAMBP
TNC
Entrez ID
80781
3678
HPRD ID
00382
00627
Ensembl ID
ENSG00000182871
ENSG00000161638
Uniprot IDs
D3DSM4
D3DSM5
P39060
P08648
PDB IDs
1BNL
3HON
3HSH
3VI3
3VI4
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Organization
Extracellular Structure Organization
Positive Regulation Of Cell-substrate Adhesion
Regulation Of Cell-substrate Adhesion
Endodermal Cell Differentiation
Catabolic Process
Angiogenesis
Endoderm Formation
Glycosaminoglycan Catabolic Process
Chondroitin Sulfate Metabolic Process
Collagen Catabolic Process
Positive Regulation Of Cell Adhesion
Anatomical Structure Formation Involved In Morphogenesis
Axon Guidance
Phototransduction, Visible Light
Collagen Metabolic Process
Blood Vessel Morphogenesis
Retinoid Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Endoderm Development
Diterpenoid Metabolic Process
Multicellular Organismal Metabolic Process
Detection Of Visible Light
Phototransduction
Extracellular Matrix Disassembly
Locomotion
Anatomical Structure Morphogenesis
Glycosaminoglycan Biosynthetic Process
Blood Vessel Development
Proteoglycan Metabolic Process
Detection Of Light Stimulus
Axonogenesis
Vasculature Development
Heparan Sulfate Proteoglycan Catabolic Process
Macrophage Apoptotic Process
Axon Development
Isoprenoid Metabolic Process
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Formation Of Primary Germ Layer
Movement Of Cell Or Subcellular Component
Regulation Of Cell Adhesion
Proteoglycan Catabolic Process
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Glycosaminoglycan Metabolic Process
Detection Of Abiotic Stimulus
Positive Regulation Of Innate Immune Response
Regulation Of Cellular Response To Growth Factor Stimulus
Gastrulation
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Cell Adhesion
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Cell Migration
Regulation Of Cell Motility
Cardiovascular System Development
Regulation Of Locomotion
Regulation Of Cellular Component Movement
Blood Vessel Development
Vasculature Development
Leukocyte Migration
Response To Stimulus
Positive Regulation Of Cell Proliferation
Wound Healing
Regulation Of Cell Proliferation
Anatomical Structure Morphogenesis
Response To Wounding
Cell-substrate Adhesion
Cell Migration
Response To Growth Factor
Movement Of Cell Or Subcellular Component
Multicellular Organismal Development
Blood Vessel Morphogenesis
Blood Coagulation
Cell Motility
Hemostasis
System Development
Anatomical Structure Development
Cellular Response To Stimulus
Locomotion
Cell Communication
Positive Regulation Of Signal Transduction
Regulation Of Signaling
Cell-matrix Adhesion
Angiogenesis
Anatomical Structure Formation Involved In Morphogenesis
Regulation Of Signal Transduction
Developmental Process
Response To Vitamin
Response To Nutrient
Regulation Of Body Fluid Levels
Signaling
Cell Activation
Regulation Of Cellular Process
Formation Of Primary Germ Layer
Signal Transduction
Tagcloud
?
936cc
ag
alter
c936t
carriers
chi
constitutes
d104n
determinant
dn
encoded
endostatin
eoc
exact
excess
fisher
frequencies
genotype
genotypes
inherited
polymorphism
preliminary
reflecting
remaining
respective
restriction
tendency
toward
vegf
Tagcloud (Difference)
?
936cc
ag
alter
c936t
carriers
chi
constitutes
d104n
determinant
dn
encoded
endostatin
eoc
exact
excess
fisher
frequencies
genotype
genotypes
inherited
polymorphism
preliminary
reflecting
remaining
respective
restriction
tendency
toward
vegf
Tagcloud (Intersection)
?