ITGA5 and AUP1

Number of citations of the paper that reports this interaction (PMID 12042322)
6

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ITGA5	AUP1
Gene Name		integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	ancient ubiquitous protein 1
Image
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Plasma Membrane Cell-cell Junction Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Ruffle Membrane Synapse Alphav-beta3 Integrin-vitronectin Complex	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Epidermal Growth Factor Receptor Binding Platelet-derived Growth Factor Receptor Binding Integrin Binding Protein Binding Vascular Endothelial Growth Factor Receptor 2 Binding Metal Ion Binding	Protein Binding
	Biological Process	Angiogenesis Cell-substrate Junction Assembly Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Integrin-mediated Signaling Pathway Axon Guidance Blood Coagulation Memory Positive Regulation Of Cell-substrate Adhesion Viral Process Extracellular Matrix Organization Positive Regulation Of Cell Migration Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-substrate Adhesion Cell-cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Wound Healing, Spreading Of Epidermal Cells Endodermal Cell Differentiation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Negative Regulation Of Anoikis
Pathways		Signal transduction by L1 Axon guidance Elastic fibre formation Fibronectin matrix formation L1CAM interactions Integrin cell surface interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ANGPT1 ANGPTL3 ARHGAP5 AUP1 CD9 COL18A1 COL1A1 EGFR ERBB2 FGFR2 FLT4 FN1 GIPC1 GRK6 ITGB1 ITGB3 ITGB5 L1CAM NISCH PECAM1 RABIF SPP1 STAMBP TNC	7 interactors: ITGA1 ITGA2 ITGA2B ITGA5 ITGAM ITGAV RNF11
Entrez ID		3678	550
HPRD ID		00627	03892
Ensembl ID		ENSG00000161638	ENSG00000115307
Uniprot IDs		P08648	Q9Y679
PDB IDs		3VI3 3VI4	2EKF
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Cell Adhesion Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cell Migration Regulation Of Cell Motility Cardiovascular System Development Regulation Of Locomotion Regulation Of Cellular Component Movement Blood Vessel Development Vasculature Development Leukocyte Migration Response To Stimulus Positive Regulation Of Cell Proliferation Wound Healing Regulation Of Cell Proliferation Anatomical Structure Morphogenesis Response To Wounding Cell-substrate Adhesion Cell Migration Response To Growth Factor Movement Of Cell Or Subcellular Component Multicellular Organismal Development Blood Vessel Morphogenesis Blood Coagulation Cell Motility Hemostasis System Development Anatomical Structure Development Cellular Response To Stimulus Locomotion Cell Communication Positive Regulation Of Signal Transduction Regulation Of Signaling Cell-matrix Adhesion Angiogenesis Anatomical Structure Formation Involved In Morphogenesis Regulation Of Signal Transduction Developmental Process Response To Vitamin Response To Nutrient Regulation Of Body Fluid Levels Signaling Cell Activation Regulation Of Cellular Process Formation Of Primary Germ Layer Signal Transduction	Integrin-mediated Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization Blood Coagulation Hemostasis Cell-substrate Adhesion Regulation Of Body Fluid Levels Wound Healing Chemotaxis Response To Wounding Axon Guidance Cell-matrix Adhesion Cell Adhesion Axonogenesis Locomotion Axon Development Cell Morphogenesis Involved In Neuron Differentiation Leukocyte Migration Neuron Projection Morphogenesis Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Neurogenesis Neuron Projection Development Cell Migration Cell Projection Morphogenesis Positive Regulation Of Cell Migration Cell Part Morphogenesis Positive Regulation Of Cell Motility Cell Development Response To External Stimulus Positive Regulation Of Cellular Component Movement Cell Motility Positive Regulation Of Locomotion Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Nervous System Development Formation Of Primary Germ Layer Cell Adhesion Mediated By Integrin Single Organismal Cell-cell Adhesion Regulation Of Cell Migration Regulation Of Cell Motility Gastrulation Heterotypic Cell-cell Adhesion Regulation Of Locomotion Generation Of Neurons Regulation Of Cellular Component Movement Cellular Extravasation Positive Regulation Of Phosphatase Activity
Tagcloud ?			abundance affects ancient associates conjugating connection cue dislocation droplet droplets endoplasmic engagement facilitates hrd1 impairs involves lipid localizes misfolded physically polyubiquitylation proteasome quality recruit reticulum sel1l ube2g2 ubiquitin ubiquitous
Tagcloud (Difference) ?			abundance affects ancient associates conjugating connection cue dislocation droplet droplets endoplasmic engagement facilitates hrd1 impairs involves lipid localizes misfolded physically polyubiquitylation proteasome quality recruit reticulum sel1l ube2g2 ubiquitin ubiquitous
Tagcloud (Intersection) ?