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ITGA5 and STAMBP
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
ITGA5
STAMBP
Description
integrin subunit alpha 5
STAM binding protein
Image
GO Annotations
Cellular Component
Ruffle
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Membrane
Cell Junction
Cytoplasmic Vesicle
Ruffle Membrane
Integrin Alpha5-beta1 Complex
Synapse
Postsynaptic Membrane
Anchoring Junction
Alphav-beta3 Integrin-vitronectin Complex
Glutamatergic Synapse
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Cytosol
Plasma Membrane
Membrane
Cleavage Furrow
Extracellular Exosome
Molecular Function
Virus Receptor Activity
Signaling Receptor Binding
Epidermal Growth Factor Receptor Binding
Platelet-derived Growth Factor Receptor Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Signaling Receptor Activity
Vascular Endothelial Growth Factor Receptor 2 Binding
Metal Ion Binding
Cell Adhesion Molecule Binding
Protein Binding
Peptidase Activity
Metallopeptidase Activity
Hydrolase Activity
Protein Domain Specific Binding
Metal Ion Binding
K63-linked Deubiquitinase Activity
Deubiquitinase Activity
Metal-dependent Deubiquitinase Activity
Biological Process
Angiogenesis
Formation Of Primary Germ Layer
Cell-substrate Junction Assembly
Cell Adhesion
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Leukocyte Cell-cell Adhesion
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Female Pregnancy
Memory
Tissue Development
Positive Regulation Of Cell-substrate Adhesion
Response To Muscle Activity
CD40 Signaling Pathway
Positive Regulation Of Cell Migration
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell-substrate Adhesion
Cell Adhesion Mediated By Integrin
Cell-cell Adhesion Mediated By Integrin
Heterotypic Cell-cell Adhesion
Wound Healing, Spreading Of Epidermal Cells
Endodermal Cell Differentiation
Regulation Of Angiogenesis
Symbiont Entry Into Host Cell
Cell-cell Adhesion
Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Positive Regulation Of Sprouting Angiogenesis
Negative Regulation Of Anoikis
Mitotic Cytokinesis
Proteolysis
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Cell Population Proliferation
Protein Deubiquitination
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Protein K63-linked Deubiquitination
Hippocampal Neuron Apoptotic Process
Negative Regulation Of Hippocampal Neuron Apoptotic Process
Pathways
Elastic fibre formation
Fibronectin matrix formation
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Integrin cell surface interactions
Signal transduction by L1
RUNX2 regulates genes involved in cell migration
GPER1 signaling
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
Metalloprotease DUBs
Drugs
Resveratrol
Tauroursodeoxycholic acid
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Anti-saccade response (
29064472
)
Bell's palsy (
33602968
)
Blood metabolite levels (
26401656
)
Serum metabolite levels (
23093944
33031748
)
Interacting Genes
32 interacting genes:
ACKR5
ANGPT1
ANGPT2
ANGPTL3
ARHGAP5
AUP1
CD9
CLK1
COL18A1
COL1A1
EGFR
ERBB2
FGFR2
FLT4
FN1
GIPC1
GRK6
ITGB1
ITGB3
ITGB5
L1CAM
LGALS3BP
NISCH
PECAM1
RABIF
SHARPIN
SPP1
STAMBP
TNC
UBAP1
VCL
VTN
51 interacting genes:
ALAS1
AMN
APOBEC3A
ATG14
BMPR1B
CASR
CHMP1A
CHMP1B
CHMP2A
CHMP3
CHMP4A
CHMP4B
CHMP4C
CHMP5
CLTC
CTNNBL1
CYP2C9
DSCR9
EGFR
EPS15
GRAP2
GRB2
IL1RL2
ITGA5
MAP2K5
MAP3K2
MLKL
NLRP7
NTPCR
PJA1
RBM11
RECQL5
RNF11
SMAD2
SMAD6
SMAD7
SNCA
SPG7
STAM
STAM2
TNFRSF1A
TP53
TRAF6
TRIP13
UACA
UBC
UBE2S
ULK1
USP21
USP28
VHL
Entrez ID
3678
10617
HPRD ID
00627
05877
Ensembl ID
ENSG00000161638
ENSG00000124356
Uniprot IDs
B2R627
P08648
A0A140VK54
A0A804HIF8
A0A804HII8
A0A804HJ64
O95630
PDB IDs
3VI3
3VI4
4WJK
4WK0
4WK2
4WK4
7NWL
7NXD
9B9J
9B9K
9CKV
2XZE
3RZU
3RZV
5IXF
Enriched GO Terms of Interacting Partners
?
Cell Adhesion
Integrin Binding
Cell-substrate Adhesion
Cell-matrix Adhesion
Regulation Of Cell Migration
Regulation Of Cell Motility
Regulation Of Locomotion
Angiogenesis
Anatomical Structure Formation Involved In Morphogenesis
Positive Regulation Of Cell Migration
Extracellular Matrix
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Cell Surface Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Cell Migration
Receptor Complex
Response To Growth Factor
Signal Transduction
Cell Adhesion Mediated By Integrin
Enzyme-linked Receptor Protein Signaling Pathway
Cell Motility
Extracellular Exosome
Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Regulation Of Response To Wounding
Regulation Of ERK1 And ERK2 Cascade
Focal Adhesion
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cell Adhesion
Extracellular Space
Negative Regulation Of Blood Coagulation
Cell Junction Organization
Negative Regulation Of Hemostasis
Negative Regulation Of Coagulation
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Transmembrane Receptor Protein Tyrosine Kinase Activity
Mesodermal Cell Differentiation
Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Wound Healing, Spreading Of Epidermal Cells
Extracellular Region
Regulation Of Cell-substrate Adhesion
Regulation Of Anatomical Structure Morphogenesis
Platelet Alpha Granule Membrane
Protein Tyrosine Kinase Activity
Positive Regulation Of Signal Transduction
Positive Regulation Of Cell Population Proliferation
Regulation Of Wound Healing
Regulation Of Cell Population Proliferation
ESCRT III Complex
Amphisome Membrane
Vesicle Fusion With Vacuole
Multivesicular Body Organization
Multivesicular Body Assembly
Multivesicular Body-lysosome Fusion
Viral Budding From Plasma Membrane
Late Endosome To Vacuole Transport
Lysosomal Membrane Organization
Endosome Transport Via Multivesicular Body Sorting Pathway
Membrane Fission
Multivesicular Body Sorting Pathway
Late Endosome To Lysosome Transport
Kinetochore Microtubule
Autophagosome Membrane
Viral Budding Via Host ESCRT Complex
Regulation Of Mitotic Spindle Assembly
Midbody Abscission
Regulation Of Mitotic Spindle Organization
Viral Budding
Nuclear Membrane Reassembly
Mitotic Cytokinetic Process
Multivesicular Body Membrane
Viral Release From Host Cell
Plasma Membrane Repair
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Autophagosome Maturation
Endosome Organization
Regulation Of Spindle Assembly
Autophagy
Cytokinetic Process
Protein-containing Complex Disassembly
Endosomal Transport
Multivesicular Body
Mitotic Metaphase Chromosome Alignment
Biological Process Involved In Interaction With Host
Nuclear Membrane Organization
Vacuolar Transport
Vacuole Organization
Metaphase Chromosome Alignment
Membrane Assembly
Endosome
Macroautophagy
Regulation Of Microtubule Cytoskeleton Organization
Chromosome Localization
Lysosomal Transport
Regulation Of Centrosome Duplication
Nuclear Pore
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Nucleus Organization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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