METTL17 and THTPA

		METTL17	THTPA
Description		methyltransferase like 17	thiamine triphosphatase
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Intracellular Organelle Lumen	Cytoplasm Cytosol
	Molecular Function	Protein Binding Methyltransferase Activity Small Molecule Binding Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Mitochondrial Ribosome Binding S-adenosyl-L-methionine Binding	Magnesium Ion Binding Protein Binding Hydrolase Activity Metal Ion Binding Thiamine Triphosphate Phosphatase Activity
	Biological Process	Translation Ribosomal Small Subunit Biogenesis Mitochondrial Small Ribosomal Subunit Assembly	Generation Of Precursor Metabolites And Energy Thiamine Metabolic Process Phosphate-containing Compound Metabolic Process Thiamine Diphosphate Biosynthetic Process Dephosphorylation Thiamine Diphosphate Metabolic Process Thiamine-containing Compound Metabolic Process
Pathways			Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS		Degraded stimulus continuous performance test score ( 31596458)
Interacting Genes		21 interacting genes: ATXN1 ATXN1L CALCOCO2 CARD10 CBY2 CEP70 KRT34 KRT40 MAPK6 MDFI MEOX2 MID2 MTUS2 NUDT16L1 NUTM1 PNMA1 SF3B4 TFIP11 TRAF1 TRIP6 VCP	1 interacting genes: TLX3
Entrez ID		64745	79178
HPRD ID		13379	15505
Ensembl ID		ENSG00000165792	ENSG00000259431
Uniprot IDs		A0A0S2Z5L8 Q9H7H0	G3V5Q5 Q9BU02
PDB IDs		8CSP 8CSQ 8CSR 8CSS 8CST 8CSU	3BHD 3TVL
Enriched GO Terms of Interacting Partners?		POZ Domain Binding Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
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