FBF1 and TRIM29

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FBF1	TRIM29
Description		Fas binding factor 1	tripartite motif containing 29
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Apical Junction Complex Keratin Filament Anchoring Junction Ciliary Transition Fiber	Cytoplasm Lysosome Adherens Junction
	Molecular Function	Protein Binding	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Cell Projection Organization Apical Junction Assembly Cilium Assembly Establishment Of Epithelial Cell Polarity	Negative Regulation Of Transcription By RNA Polymerase II Immune System Process Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus
Pathways		Anchoring of the basal body to the plasma membrane	Interferon gamma signaling
Drugs
Diseases
GWAS		Age-related hearing impairment ( 34108613) Coronary artery disease ( 29212778) White matter hyperintensities ( 30002152) White matter hyperintensity burden ( 25663218)	Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)
Interacting Genes		50 interacting genes: ABI3 ACCS APP BLZF1 CALCOCO2 CCDC102B CCDC85B CEP55 CEP63 CINP CLK1 DEUP1 DGCR6 FAS FBXL12 GATA1 GCC1 GOLGA2 HIF1AN IFT20 IKZF3 KRT13 KRT31 KRT40 MEOX2 MID2 MIPOL1 PNMA1 RBPMS RHOXF2 SSX2IP SUMO1 TADA2A TASOR2 TCEA2 TEX11 TLE5 TMCC2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM29 TRIM54 TSC1 TSGA10 TTC32 TUBGCP4 USHBP1 VPS37B	55 interacting genes: ACTN3 ANKS1A ATM CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF13 RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM
Entrez ID		85302	23650
HPRD ID		10948	10280
Ensembl ID		ENSG00000188878	ENSG00000137699
Uniprot IDs		Q8TES7	B7Z5V5 B7Z8U9 E9PRL4 Q14134
PDB IDs			2CSV
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Centriole Cytoskeleton De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Microtubule Organizing Center Organization De Novo Centriole Assembly	Negative Regulation Of Viral Transcription Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-protein Transferase Activity Nucleus Cytoskeleton Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Viral Transcription Regulation Of Skeletal Muscle Fiber Development Protein Ubiquitination Positive Regulation Of DNA Recombination Cytosol Positive Regulation Of Metabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Development Somatic Cell DNA Recombination Cytoplasm Ubiquitin Protein Ligase Activity Positive Regulation Of Autophagy Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA Recombination Signal Transduction By P53 Class Mediator Suppression Of Viral Release By Host Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Ligase Complex Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Intracellular Signal Transduction Double-strand Break Repair Via Nonhomologous End Joining Nucleoplasm Protein Modification Process Guanine/thymine Mispair Binding Positive Regulation Of Biosynthetic Process Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Positive Regulation Of Catabolic Process Protein Localization To Site Of Double-strand Break Positive Regulation Of Cell Development Regulation Of DNA Recombination Somatic Diversification Of Immunoglobulins Involved In Immune Response Regulation Of RNA Metabolic Process Negative Regulation Of Viral Process Macromolecule Catabolic Process Identical Protein Binding Protein Binding Signal Transduction In Response To DNA Damage Transcription Regulator Complex Positive Regulation Of Isotype Switching To IgA Isotypes
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