FBF1 and ACCS

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FBF1	ACCS
Description		Fas binding factor 1	1-aminocyclopropane-1-carboxylate synthase homolog (inactive)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Apical Junction Complex Keratin Filament Anchoring Junction Ciliary Transition Fiber
	Molecular Function	Protein Binding	Protein Binding Transaminase Activity 1-aminocyclopropane-1-carboxylate Synthase Activity Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	Cell Projection Organization Apical Junction Assembly Cilium Assembly Establishment Of Epithelial Cell Polarity	Amino Acid Metabolic Process
Pathways		Anchoring of the basal body to the plasma membrane
Drugs			Vinylglycine
Diseases
GWAS		Age-related hearing impairment ( 34108613) Coronary artery disease ( 29212778) White matter hyperintensities ( 30002152) White matter hyperintensity burden ( 25663218)	IgA nephropathy ( 26028593)
Interacting Genes		50 interacting genes: ABI3 ACCS APP BLZF1 CALCOCO2 CCDC102B CCDC85B CEP55 CEP63 CINP CLK1 DEUP1 DGCR6 FAS FBXL12 GATA1 GCC1 GOLGA2 HIF1AN IFT20 IKZF3 KRT13 KRT31 KRT40 MEOX2 MID2 MIPOL1 PNMA1 RBPMS RHOXF2 SSX2IP SUMO1 TADA2A TASOR2 TCEA2 TEX11 TLE5 TMCC2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM29 TRIM54 TSC1 TSGA10 TTC32 TUBGCP4 USHBP1 VPS37B	3 interacting genes: CFTR FBF1 UQCRB
Entrez ID		85302	84680
HPRD ID		10948	10524
Ensembl ID		ENSG00000188878	ENSG00000110455
Uniprot IDs		Q8TES7	A0A0S2Z622 Q96QU6
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Centriole Cytoskeleton De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Microtubule Organizing Center Organization De Novo Centriole Assembly	Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Amelogenesis Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Respiratory Chain Complex III Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Respiratory Chain Complex Apical Junction Assembly Ciliary Transition Fiber Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Oxidative Phosphorylation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Establishment Of Epithelial Cell Polarity Apical Junction Complex Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP
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