TNIP3 and TAX1BP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TNIP3	TAX1BP1
Gene Name		TNFAIP3 interacting protein 3	Tax1 (human T-cell leukemia virus type I) binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol Extracellular Vesicular Exosome
	Molecular Function	Polyubiquitin Binding	Protein Binding Kinase Binding
	Biological Process	MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Lipopolysaccharide	Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process Innate Immune Response
Pathways			RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling Innate Immune System
Drugs
Diseases
GWAS		Breast cancer ( 23468962)
Protein-Protein Interactions		11 interactors: DAZAP2 KRT40 KRTAP10-3 KRTAP10-8 LZTS2 NOTCH2NL TAX1BP1 TNFAIP3 TNIP1 UBC ZBTB8A	40 interactors: ARHGAP1 CALCOCO2 CNTN2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN EMILIN1 FAM168A FAM189A2 FOXC2 GABARAP IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP1 TNIP3 TRAF6 TSG101 TSHZ3 UBC
Entrez ID		79931	8887
HPRD ID		16268	05618
Ensembl ID		ENSG00000050730	ENSG00000106052
Uniprot IDs		Q96KP6	A4D196 B4DSG5 Q86VP1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type I Interferon Production Regulation Of Type I Interferon Production Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Negative Regulation Of Cytokine Production Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Innate Immune Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Signal Transduction Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Signaling MyD88-dependent Toll-like Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Negative Regulation Of CD40 Signaling Pathway Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Defense Response Regulation Of Cytokine Production Negative Regulation Of Protein Ubiquitination Toll-like Receptor Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Osteoclast Proliferation Tolerance Induction To Lipopolysaccharide Positive Regulation Of Immune Response Notch Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Regulation Of CD40 Signaling Pathway Protein Polyubiquitination Regulation Of Vascular Wound Healing Positive Regulation Of Hepatocyte Proliferation Negative Regulation Of Chronic Inflammatory Response Innate Immune Response Negative Regulation Of Wnt Signaling Pathway Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Regulation Of Immune Response Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway B-1 B Cell Homeostasis Positive Regulation Of Protein Catabolic Process Positive Regulation Of Immune System Process	Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling MyD88-independent Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Organelle Disassembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Nucleophagy Immune Response-regulating Signaling Pathway JNK Cascade Cellular Response To Stress Mitochondrion Degradation Regulation Of Vascular Wound Healing Regulation Of Type I Interferon Production Stress-activated MAPK Cascade Negative Regulation Of Intracellular Signal Transduction Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Autophagic Vacuole Assembly Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Macroautophagy Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Autophagy Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Protein Processing Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Membrane Organization
Tagcloud ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Difference) ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Intersection) ?