TNIP3 and DAZAP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TNIP3	DAZAP2
Gene Name		TNFAIP3 interacting protein 3	DAZ associated protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Polyubiquitin Binding	Protein Binding WW Domain Binding
	Biological Process	MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23468962)
Protein-Protein Interactions		11 interactors: DAZAP2 KRT40 KRTAP10-3 KRTAP10-8 LZTS2 NOTCH2NL TAX1BP1 TNFAIP3 TNIP1 UBC ZBTB8A	86 interactors: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FAM46B FAM46C FBN3 GPSM1 HGS HIP1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MED31 NDUFA5 NEDD4 NEDD4L NOC4L OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPT2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581
Entrez ID		79931	9802
HPRD ID		16268	08463
Ensembl ID		ENSG00000050730	ENSG00000183283
Uniprot IDs		Q96KP6	E9PB45 Q15038
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type I Interferon Production Regulation Of Type I Interferon Production Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Negative Regulation Of Cytokine Production Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Innate Immune Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Signal Transduction Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Signaling MyD88-dependent Toll-like Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Negative Regulation Of CD40 Signaling Pathway Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Defense Response Regulation Of Cytokine Production Negative Regulation Of Protein Ubiquitination Toll-like Receptor Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Osteoclast Proliferation Tolerance Induction To Lipopolysaccharide Positive Regulation Of Immune Response Notch Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Regulation Of CD40 Signaling Pathway Protein Polyubiquitination Regulation Of Vascular Wound Healing Positive Regulation Of Hepatocyte Proliferation Negative Regulation Of Chronic Inflammatory Response Innate Immune Response Negative Regulation Of Wnt Signaling Pathway Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Regulation Of Immune Response Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway B-1 B Cell Homeostasis Positive Regulation Of Protein Catabolic Process Positive Regulation Of Immune System Process	Negative Regulation Of Signal Transduction Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Protein Processing Regulation Of ERBB Signaling Pathway Protein Ubiquitination Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Polyubiquitination Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Response To Transforming Growth Factor Beta Virion Assembly Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Signaling Intracellular Transport Of Virus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Protein Metabolic Process RNA Biosynthetic Process Endosomal Transport Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type I Interferon Production Transforming Growth Factor Beta Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
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