TNIP3 and MAGEA2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNIP3	MAGEA2B
Description		TNFAIP3 interacting protein 3	MAGE family member A2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus PML Body
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding
	Biological Process	MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Transcription By RNA Polymerase II Inflammatory Response Toll-like Receptor 4 Signaling Pathway Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Canonical NF-kappaB Signal Transduction Cellular Response To Lipopolysaccharide	Negative Regulation Of Transcription By RNA Polymerase II Protein Catabolic Process Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation
Pathways		Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Breast cancer ( 23468962) Multiple sclerosis ( 31604244)
Interacting Genes		25 interacting genes: CCN3 CYSRT1 DAZAP2 FAM161A KPNA3 KRT40 KRTAP10-3 KRTAP10-8 LITAF LZTS2 MAGEA2 MAGEA2B MTUS2 NBPF19 NOTCH2NLA NTAQ1 PIBF1 PLSCR3 TAX1BP1 TCEANC TNIP1 TRIM55 TRIM63 UBC ZBTB8A	24 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 CEP57L1 COQ4 COX7C DYNLRB1 KRT8P12 MBD3 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TRIM28 TRIM31 TUBB ZNF655
Entrez ID		79931	266740
HPRD ID		16268	14347
Ensembl ID		ENSG00000050730	ENSG00000183305
Uniprot IDs		Q96KP6	P43356
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Acetylation Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity
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