MCMBP and PRTFDC1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MCMBP	PRTFDC1
Gene Name		minichromosome maintenance complex binding protein	phosphoribosyl transferase domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane MCM Complex	Cytosol
	Molecular Function	Chromatin Binding Protein Binding	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Homodimerization Activity
	Biological Process	DNA-dependent DNA Replication Sister Chromatid Cohesion Mitotic Nuclear Division Cell Division	Purine Ribonucleoside Salvage Adenine Salvage Guanine Salvage GMP Salvage IMP Salvage GMP Catabolic Process Hypoxanthine Metabolic Process
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: DDIT3 MCM7 PRTFDC1 USP7	12 interactors: DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B MCMBP NIF3L1 STAT5A TCL1A
Entrez ID		79892	56952
HPRD ID		07624	17917
Ensembl ID		ENSG00000197771	ENSG00000099256
Uniprot IDs		Q9BTE3	Q9NRG1
PDB IDs			2JBH
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Determination Of Dorsal Identity Regulation Of Transcription Involved In Anterior/posterior Axis Specification Cellular Response To Stress Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Maintenance Of DNA Methylation ER Overload Response Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process MRNA Transcription From RNA Polymerase II Promoter DNA Unwinding Involved In DNA Replication Proteolysis Involved In Cellular Protein Catabolic Process Blood Vessel Maturation Cellular Protein Catabolic Process MRNA Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Protein Catabolic Process Histone Deubiquitination Negative Regulation Of Myoblast Differentiation Cellular Response To Epidermal Growth Factor Stimulus Response To Stress Response To Epidermal Growth Factor DNA Strand Elongation Involved In DNA Replication Cellular Macromolecule Catabolic Process DNA Strand Elongation Positive Regulation Of Interleukin-8 Production DNA Replication Initiation Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Sequestering Of Calcium Ion Transcription-coupled Nucleotide-excision Repair Regulation Of Myoblast Differentiation Chromosome Organization Negative Regulation Of Muscle Cell Differentiation Cell Cycle Process Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport DNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Regulation Of DNA-templated Transcription In Response To Stress Nucleobase-containing Compound Metabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Heterocycle Metabolic Process	Positive Regulation Of Mast Cell Differentiation GMP Salvage GMP Catabolic Process Guanine Salvage Glucosamine Catabolic Process FAD Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Regulation Of Mast Cell Differentiation Adenine Salvage Dihydrobiopterin Metabolic Process Hypoxanthine Salvage Development Of Secondary Male Sexual Characteristics Positive Regulation Of Dopamine Metabolic Process Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Negative Regulation Of Mast Cell Apoptotic Process GMP Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity Creatinine Metabolic Process Regulation Of Mast Cell Apoptotic Process Purine Nucleoside Monophosphate Catabolic Process Glucosamine Metabolic Process Positive Regulation Of Mast Cell Proliferation Riboflavin Metabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Purine Ribonucleoside Salvage Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Response To Organonitrogen Compound Heterocycle Metabolic Process Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway GMP Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics Valine Metabolic Process Creatine Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Natural Killer Cell Differentiation Succinate Metabolic Process Regulation Of Glycogen (starch) Synthase Activity Regulation Of Gamma-delta T Cell Differentiation Development Of Secondary Sexual Characteristics Purine Ribonucleoside Catabolic Process Luteinization Positive Regulation Of Glycogen Biosynthetic Process
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