LSM2 and RSRC1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		LSM2	RSRC1
Gene Name		LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	arginine/serine-rich coiled-coil 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol Catalytic Step 2 Spliceosome	Nucleus Cytoplasm Nuclear Speck
	Molecular Function	Protein Binding U6 SnRNA Binding Ral GTPase Binding Protein Kinase Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Protein Phosphorylation Nucleocytoplasmic Transport RNA Splicing Response To Antibiotic
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS			Height ( 23563607)
Protein-Protein Interactions		31 interactors: AES BANP C14orf1 CLNS1A CRMP1 DDX20 DNAJA1 EXOSC10 GBP2 KRT13 LNX1 LSM1 LSM3 LSM5 LSM6 LSM7 LSM8 MAGEA6 MEOX2 PRCC RALA REL RSRC1 SF3B2 SMN1 SNRPB SNRPD2 SNRPE TRIM54 ZBTB16 ZNF408	8 interactors: ACTR3B EEF1A1 GDF9 JMJD6 LSM2 SRPK1 SRPK2 UTP14A
Entrez ID		57819	51319
HPRD ID		06282	18006
Ensembl ID		ENSG00000204392	ENSG00000174891
Uniprot IDs		Q9Y333	Q96IZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Metabolic Process MRNA Processing RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Splicing, Via Spliceosome RNA Metabolic Process Spliceosomal SnRNP Assembly Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Histone MRNA Metabolic Process Nitrogen Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Ribonucleoprotein Complex Assembly RNA Catabolic Process NcRNA Metabolic Process Aromatic Compound Catabolic Process Histone MRNA Catabolic Process Spliceosomal Complex Assembly Cellular Metabolic Process Cellular Macromolecule Catabolic Process Cellular Macromolecular Complex Assembly Metabolic Process Termination Of RNA Polymerase II Transcription Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Catabolic Process DNA-templated Transcription, Termination Transcription From RNA Polymerase II Promoter MRNA 3'-end Processing Membrane Raft Localization Positive Regulation Of Anoikis Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Embryonic Pattern Specification Cellular Process Positive Regulation Of Apoptotic Process Positive Regulation Of NK T Cell Differentiation Positive Regulation Of Programmed Cell Death Transcription, DNA-templated Positive Regulation Of Cell Death Male Germ-line Stem Cell Asymmetric Division Somite Specification	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Splicing Regulation Of RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication RNA Metabolic Process Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Nuclear Speck Organization Oocyte Growth Nucleus Organization Nucleobase-containing Compound Metabolic Process Regulation Of Viral Process Heterocycle Metabolic Process Regulation Of Progesterone Secretion Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Recognition Of Apoptotic Cell MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process Germ Cell Development Sperm Chromatin Condensation Regulation Of Female Gonad Development Ribonucleoprotein Complex Biogenesis Angiogenesis Phagocytosis, Recognition Regulation Of RNA Metabolic Process Blood Vessel Morphogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Cellular Response To Epidermal Growth Factor Stimulus Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Protein Hydroxylation Spermatid Nucleus Differentiation Response To Epidermal Growth Factor Macrophage Activation Maturation Of SSU-rRNA Apoptotic Cell Clearance
Tagcloud ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm23 lsm5 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal	breakpoint call combines comparisons complexity computational discordance frame fusions inversion libraries maml2 mate nasopharyngeal npc pair ptk2 ptplb reads rearrangements reconstruction recurrently sanger smash somatic sp3 split structural yap1
Tagcloud (Difference) ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm23 lsm5 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal	breakpoint call combines comparisons complexity computational discordance frame fusions inversion libraries maml2 mate nasopharyngeal npc pair ptk2 ptplb reads rearrangements reconstruction recurrently sanger smash somatic sp3 split structural yap1
Tagcloud (Intersection) ?